{"id":5195,"date":"2024-03-29T13:00:00","date_gmt":"2024-03-29T17:00:00","guid":{"rendered":"https:\/\/stillcoviding.ca\/en\/?p=5195"},"modified":"2024-03-29T23:54:10","modified_gmt":"2024-03-30T03:54:10","slug":"covid-19-research-study-reveals-new-details-about-potentially-deadly-inflammation","status":"publish","type":"post","link":"https:\/\/stillcoviding.ca\/en\/news\/covid-19-research-study-reveals-new-details-about-potentially-deadly-inflammation\/","title":{"rendered":"COVID-19 research: Study reveals new details about potentially deadly inflammation"},"content":{"rendered":"<p>A recent USC study provides new information about why SARS-CoV-2, the virus behind the COVID-19 pandemic, may elicit mild symptoms at first but then, for a subset of patients, turn potentially fatal a week or so after infection. The researchers showed that distinct stages of illness correspond with the coronavirus acting differently in two different populations of cells.<\/p>\n<p>The study, published in <em><a href=\"https:\/\/www.nature.com\/articles\/s41556-024-01388-w\" target=\"_blank\" lang=\"en\" rel=\"noopener\">Nature Cell Biology<\/a><\/em>, may provide a roadmap for addressing cytokine storms and other excessive immune reactions that drive serious COVID-19.<\/p>\n<p>The team found that when SARS-CoV-2 infects its first-phase targets, cells in the lining of the lung, two viral proteins circulate within those cells\u2014one that works to activate the immune system and a second that, paradoxically, blocks that signal, resulting in little or no inflammation.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A recent USC study provides new information about why SARS-CoV-2, the virus behind the COVID-19 pandemic, may elicit mild symptoms at first but then, for a subset of patients, turn potentially fatal a week or so after infection. The researchers showed that distinct stages of illness correspond with the coronavirus acting differently in two different populations of cells.<\/p>\n<p>The study, published in <em><a href=\"https:\/\/www.nature.com\/articles\/s41556-024-01388-w\" target=\"_blank\" lang=\"en\" rel=\"noopener\">Nature Cell Biology<\/a><\/em>, may provide a roadmap for addressing cytokine storms and other excessive immune reactions that drive serious COVID-19.<\/p>\n<p>The team found that when SARS-CoV-2 infects its first-phase targets, cells in the lining of the lung, two viral proteins circulate within those cells\u2014one that works to activate the immune system and a second that, paradoxically, blocks that signal, resulting in little or no inflammation.<\/p>\n<div class=\"more-link-wrapper\"><a class=\"more-link\" href=\"https:\/\/stillcoviding.ca\/en\/news\/covid-19-research-study-reveals-new-details-about-potentially-deadly-inflammation\/\">Continue reading<span class=\"screen-reader-text\">COVID-19 research: Study reveals new details about potentially deadly inflammation<\/span><\/a><\/div>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[18,1002,481,203,67,1003,1000,1001,8,14,1004],"class_list":["post-5195","post","type-post","status-publish","format-standard","hentry","category-news","tag-covid-19","tag-cytokine-storms","tag-cytokines","tag-immune-system","tag-inflammation","tag-keck-school-of-medicine","tag-nsp14","tag-orf6","tag-research","tag-sars-cov-2","tag-university-of-southern-california","entry"],"_links":{"self":[{"href":"https:\/\/stillcoviding.ca\/en\/wp-json\/wp\/v2\/posts\/5195","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/stillcoviding.ca\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/stillcoviding.ca\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/stillcoviding.ca\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/stillcoviding.ca\/en\/wp-json\/wp\/v2\/comments?post=5195"}],"version-history":[{"count":2,"href":"https:\/\/stillcoviding.ca\/en\/wp-json\/wp\/v2\/posts\/5195\/revisions"}],"predecessor-version":[{"id":5197,"href":"https:\/\/stillcoviding.ca\/en\/wp-json\/wp\/v2\/posts\/5195\/revisions\/5197"}],"wp:attachment":[{"href":"https:\/\/stillcoviding.ca\/en\/wp-json\/wp\/v2\/media?parent=5195"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/stillcoviding.ca\/en\/wp-json\/wp\/v2\/categories?post=5195"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/stillcoviding.ca\/en\/wp-json\/wp\/v2\/tags?post=5195"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}