{"id":9627,"date":"2026-01-12T16:43:00","date_gmt":"2026-01-12T21:43:00","guid":{"rendered":"https:\/\/stillcoviding.ca\/en\/?p=9627"},"modified":"2026-01-14T00:37:52","modified_gmt":"2026-01-14T05:37:52","slug":"moderna-covid-vaccine-53-effective-against-adult-hospitalization-in-2024-25-season-data-suggest","status":"publish","type":"post","link":"https:\/\/stillcoviding.ca\/en\/news\/moderna-covid-vaccine-53-effective-against-adult-hospitalization-in-2024-25-season-data-suggest\/","title":{"rendered":"Moderna COVID vaccine 53% effective against adult hospitalization in 2024-25 season, data suggest"},"content":{"rendered":"<p>A large observational <a href=\"https:\/\/link.springer.com\/article\/10.1007\/s40121-025-01292-2\" target=\"_blank\" lang=\"en\" rel=\"noreferrer noopener\">study<\/a> using US healthcare claims and electronic health record data suggests that Moderna\u2019s updated 2024-25 COVID vaccine was 39% effective at preventing medically attended illness among adults and 53% effective against hospitalization, particularly those at high risk for severe disease.<\/p>\n<p>The study, led by scientists from the vaccine manufacturer and published late last week in <em>Infectious Diseases and Therapy<\/em>, analyzed outcomes among 596,248 adults who received the updated mRNA-1273 vaccine, which targeted the Omicron&nbsp;KP.2 variant, from August&nbsp;2024 to April&nbsp;2025. Vaccinated people were matched 1:1 with unvaccinated counterparts.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A large observational <a href=\"https:\/\/link.springer.com\/article\/10.1007\/s40121-025-01292-2\" target=\"_blank\" lang=\"en\" rel=\"noreferrer noopener\">study<\/a> using US healthcare claims and electronic health record data suggests that Moderna\u2019s updated 2024-25 COVID vaccine was 39% effective at preventing medically attended illness among adults and 53% effective against hospitalization, particularly those at high risk for severe disease.<\/p>\n<p>The study, led by scientists from the vaccine manufacturer and published late last week in <em>Infectious Diseases and Therapy<\/em>, analyzed outcomes among 596,248 adults who received the updated mRNA-1273 vaccine, which targeted the Omicron&nbsp;KP.2 variant, from August&nbsp;2024 to April&nbsp;2025. Vaccinated people were matched 1:1 with unvaccinated counterparts.<\/p>\n<div class=\"more-link-wrapper\"><a class=\"more-link\" href=\"https:\/\/stillcoviding.ca\/en\/news\/moderna-covid-vaccine-53-effective-against-adult-hospitalization-in-2024-25-season-data-suggest\/\">Continue reading<span class=\"screen-reader-text\">Moderna COVID vaccine 53% effective against adult hospitalization in 2024-25 season, data suggest<\/span><\/a><\/div>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[18,253,593,8,14,917,15],"class_list":["post-9627","post","type-post","status-publish","format-standard","hentry","category-news","tag-covid-19","tag-moderna","tag-mrna-vaccines","tag-research","tag-sars-cov-2","tag-vaccine-effectiveness","tag-vaccines","entry"],"_links":{"self":[{"href":"https:\/\/stillcoviding.ca\/en\/wp-json\/wp\/v2\/posts\/9627","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/stillcoviding.ca\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/stillcoviding.ca\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/stillcoviding.ca\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/stillcoviding.ca\/en\/wp-json\/wp\/v2\/comments?post=9627"}],"version-history":[{"count":1,"href":"https:\/\/stillcoviding.ca\/en\/wp-json\/wp\/v2\/posts\/9627\/revisions"}],"predecessor-version":[{"id":9628,"href":"https:\/\/stillcoviding.ca\/en\/wp-json\/wp\/v2\/posts\/9627\/revisions\/9628"}],"wp:attachment":[{"href":"https:\/\/stillcoviding.ca\/en\/wp-json\/wp\/v2\/media?parent=9627"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/stillcoviding.ca\/en\/wp-json\/wp\/v2\/categories?post=9627"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/stillcoviding.ca\/en\/wp-json\/wp\/v2\/tags?post=9627"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}