{"id":10046,"date":"2026-01-19T11:04:00","date_gmt":"2026-01-19T16:04:00","guid":{"rendered":"https:\/\/stillcoviding.ca\/fr\/?p=10046"},"modified":"2026-01-19T21:25:17","modified_gmt":"2026-01-20T02:25:17","slug":"post-covid-brain-fog-linked-to-elevated-ptau-181","status":"publish","type":"post","link":"https:\/\/stillcoviding.ca\/fr\/nouvelles\/post-covid-brain-fog-linked-to-elevated-ptau-181\/","title":{"rendered":"Post-COVID Brain Fog Linked to Elevated pTau-181"},"content":{"rendered":"

De nouvelles preuves issues d\u2019une \u00e9tude de cohorte prospective sugg\u00e8rent qu\u2019un taux \u00e9lev\u00e9 de tau phosphoryl\u00e9 plasmatique (pTau-181) pourrait \u00eatre un biomarqueur essentiel chez les patient\u00b7e\u00b7s souffrant de s\u00e9quelles neurologiques post-aigu\u00ebs de la COVID-19 (N-PASC), en particulier chez les travailleur\u00b7euses essentiel\u00b7le\u00b7s.<\/p>\n

N-PASC and pTau-181: Key Biomarker Insights<\/h2>\n

Researchers followed 227 essential workers who developed COVID-19<\/a> and subsequently experienced N-PASC, comparing them with 227 demographically matched controls who either recovered without neurological symptoms or did not contract the virus. Using single molecular analysis, the study measured changes in neurological biomarkers including pTau-181, glial fibrillary acidic protein (GFAP), neurofilament light chain (NfL), and amyloid beta (A\u03b240\/42 and total A\u03b2 burden, IAB).<\/p>\n

Significant Increases in pTau-181 Post-COVID<\/h2>\n

The findings revealed a striking 59.3% increase in plasma pTau-181 levels among participants with N-PASC following COVID-19 onset, with the greatest elevations in those reporting persistent central nervous system symptoms, commonly described as brain fog, cognitive difficulties, and loss of taste or smell, lasting 18 months or more. In contrast, GFAP and NfL reductions were linked to peripheral neurological symptoms, suggesting distinct biomarker profiles depending on symptom localisation.<\/p>\n","protected":false},"excerpt":{"rendered":"

NEW evidence from a prospective cohort study suggests that elevated plasma phosphorylated tau (pTau-181) may be a critical biomarker in patients experiencing neurological post-acute sequelae of COVID-19 (N-PASC), particularly among essential workers.<\/p>\n

Lire la suitePost-COVID Brain Fog Linked to Elevated pTau-181<\/span><\/a><\/div>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[10,16,42,7,12],"class_list":["post-10046","post","type-post","status-publish","format-standard","hentry","category-nouvelles","tag-covid-longue","tag-covid-19","tag-problemes-cognitifs","tag-recherche","tag-sras-cov-2","entry"],"_links":{"self":[{"href":"https:\/\/stillcoviding.ca\/fr\/wp-json\/wp\/v2\/posts\/10046","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/stillcoviding.ca\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/stillcoviding.ca\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/stillcoviding.ca\/fr\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/stillcoviding.ca\/fr\/wp-json\/wp\/v2\/comments?post=10046"}],"version-history":[{"count":2,"href":"https:\/\/stillcoviding.ca\/fr\/wp-json\/wp\/v2\/posts\/10046\/revisions"}],"predecessor-version":[{"id":10049,"href":"https:\/\/stillcoviding.ca\/fr\/wp-json\/wp\/v2\/posts\/10046\/revisions\/10049"}],"wp:attachment":[{"href":"https:\/\/stillcoviding.ca\/fr\/wp-json\/wp\/v2\/media?parent=10046"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/stillcoviding.ca\/fr\/wp-json\/wp\/v2\/categories?post=10046"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/stillcoviding.ca\/fr\/wp-json\/wp\/v2\/tags?post=10046"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}