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CAMH study confirms ongoing brain inflammation associated with long COVID

A new Centre for Addiction and Mental Health (CAMH) study found elevated levels of inflammation in the brains of patients who report persistent symptoms of long COVID.

Using advanced brain scanning with positron emission tomography (PET), the researchers found elevated levels of the protein TSPO, a brain marker of inflammation, in patients with onset of depression within several months after a COVID-19 infection.

Braga J, Lepra M, Kish SJ, et al. Neuroinflammation After COVID-19 With Persistent Depressive and Cognitive Symptoms. JAMA Psychiatry. 2023;80(8):787–795. DOI: 10.1001/jamapsychiatry.2023.1321