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Some seniors infected with Omicron variants were more susceptible to reinfection, not less: McMaster study

In a sign that scientists still don’t fully understand how some COVID-19 variants manage to evade the immune system, a new Ontario study has found that retirement- and long-term-care home residents infected during the first Omicron wave were 20 times more likely to get reinfected by the virus than those who avoided a prior infection.

The surprising finding by researchers at McMaster University runs counter to the prevailing wisdom that a previous COVID infection affords protection against future infections, at least in the older adults who participated in the study.

Early Omicron infection is associated with increased reinfection risk in older adults in long-term care and retirement facilities. Breznik, Jessica A. et al. eClinicalMedicine, 102148. DOI: 10.1016/j.eclinm.2023.102148
https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(23)00325-5/fulltext