Tag: COVID-19

Published by: CIDRAP
Published on: August 6, 2025
By Mary Van Beusekom

In what experts say will hobble pandemic preparedness, US Health and Human Services (HHS) Secretary Robert F. Kennedy Jr. yesterday announced the dismantling of the country’s mRNA vaccine-development programs—the same innovation that allowed rapid scale-up of COVID-19 vaccines during the public health emergency.

The Biomedical Advanced Research and Development Authority (BARDA) is terminating 22 mRNA vaccine-development contracts totaling just under $500 million, including an award to Moderna/University of Texas Medical Branch for a vaccine against the H5N1 avian flu now sweeping the world. That grant was terminated in late May.

Contracts awarded to Emory University and Tiba Biotech were cancelled, and agreements with Luminary Labs, ModeX, and Seqirus have been scaled back.

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pro-virus policies

RFK Jr. pulls $500 million in funding for vaccine development

Published August 6, 2025

Published by: The Associated Press
Published on: August 6, 2025
By Amanda Seitz

WASHINGTON (AP) — The Department of Health and Human Services will cancel contracts and pull funding for some vaccines that are being developed to fight respiratory viruses like COVID-19 and the flu.

Robert F. Kennedy Jr. announced in a statement Tuesday that 22 projects, totaling $500 million, to develop vaccines using mRNA technology will be halted.

Kennedy’s decision to terminate the projects is the latest in a string of decisions that have put the longtime vaccine critic’s doubts about shots into full effect at the nation’s health department. Kennedy has pulled back recommendations around the COVID-19 shots, fired the panel that makes vaccine recommendations, and refused to offer a vigorous endorsement of vaccinations as a measles outbreak worsened.

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Alberta

Alberta’s Perverse New Barriers to COVID Vaccines

Published August 5, 2025

Published by: The Tyee
Published on: August 5, 2025
By Andrew Nikiforuk

Alberta Premier Danielle Smith’s radical new rules for COVID immunization pose a genuine threat to the elderly, the working poor and pregnant moms.

Smith, who revived her ailing political career by peddling conspiratorial COVID theories, has designed a program that is not only punitive but discriminatory, bureaucratic and Soviet in nature.

“This policy is so bad that it’s actually worse than their usual failure to plan properly,” said James Talbot, the province’s former chief medical officer of health. “In fact, it is so bad it looks like they are actually planning to fail.”

Here are the three basic tenets of any successful public health program: make it available, make it accessible and make it affordable. Smith turns all three upside down.

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vaccines

Analysis: 2024-25 COVID vaccines offered strong protection against worst outcomes in seniors

Published July 31, 2025

Published by: CIDRAP
Published on: July 31, 2025
By Stephanie Soucheray

The 2024-25 COVID mRNA vaccines targeting JN.1 were highly effective in protecting against hospitalization and death for at least 4 months in a cohort of Danish citizens aged 65 and older by October 1, 2024. The new analysis estimating the vaccine efficacy (VE) of last season’s COVID vaccines was published earlier this week in The Lancet Infectious Diseases.

In total, 894,560 Danish residents were included in the study, with a median age of 76. By Jan 31, 2025, 820,229 (91.7%) of the participants had received a JN.1 vaccine. Among those without updated JN.1 vaccination (74,331), 278 COVID-19 hospitalizations and 84 deaths were observed during 25.6 million person-days.

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long COVID

Biological causes of long COVID discovered: the virus persists for months in the brain

Published July 31, 2025

Published by: Sciences et Avenir
Published on: July 31, 2025
By Camille Gaubert

Long COVID, often attributed to a psychosomatic mechanism, has biological causes, a study reveals. Months after the infection, the virus was still active, at low levels, in the brainstem of hamsters.

“We hope to bring relief to the patients who may have heard that they are not sick, that it is ‘in their heads.’ What we are showing in the laboratory is that long COVID has a biological cause!,” says Guilherme Dias de Melo, a veterinarian and researcher in infectious diseases and neuropathologies at the Institut Pasteur. Eighty days after the initial infection, the COVID-19 virus was found, still infectious, in the brainstems of hamsters affected by symptoms similar to those of long COVID, according to the work that he has directed and published in the journal Nature Communications.

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cancer

COVID infection early in pandemic linked to higher risk of cancer death, CU study finds

Published July 30, 2025

Published by: The Denver Post
Published on: July 30, 2025
By Meg Wingerter

Cancer survivors infected with COVID-19 in the early months of the pandemic had a higher risk of dying from dormant cells reawakening, Colorado researchers found, though they don’t know whether people who get the virus now face the same risk.

Experiments in mice found that genetically modified animals were more likely to have signs of metastatic cancer in their lungs if infected with flu or COVID-19 than engineered mice that researchers didn’t give a virus, said James DeGregori, deputy director of the University of Colorado Cancer Center in Aurora.

That finding launched an international partnership to determine whether the same thing happened in people, he said.

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cancer

‘Sleeping’ cancer cells in the lungs can be roused by COVID and flu

Published July 30, 2025

Published by: Nature
Published on: July 30, 2025
By Max Kozlov

Hidden in the lungs of some breast cancer survivors are tumour cells that can remain dormant for decades — until they one day trigger a relapse. Now, experiments in mice show that these rogue cells can be roused from their slumber by common respiratory illnesses such as COVID-19 or the flu.

The findings, published in Nature on 30 July¹, seem to extend to humans too: data from thousands of people show that infection with the coronavirus SARS-CoV-2 is linked with a nearly twofold increase in cancer-related death, possibly helping to explain why cancer death rates increased early during the COVID-19 pandemic.

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Trump regime

Controversial FDA official Dr. Vinay Prasad departs agency

Published July 29, 2025

Published by: CNN
Published on: July 29, 2025
By Meg Tirrell, Sarah Owermohle, Adam Cancryn

Dr. Vinay Prasad, the controversial critic of the US Food and Drug Administration who took a top role at the regulatory agency in May, has resigned less than three months into the job.

“Dr. Prasad did not want to be a distraction to the great work of the FDA in the Trump administration and has decided to return to California and spend more time with his family,” a spokesperson for the US Department of Health and Human Services told CNN on Tuesday.

Prasad, a hematologist oncologist, was named head of the FDA’s Center for Biologics Evaluation and Research in early May, giving him purview over vaccines and biologic medicines. He was subsequently also given the role of FDA chief medical and scientific officer. Like a number of Trump administration health appointees, Prasad had been a harsh critic of the government’s response and vaccine policies during the Covid-19 pandemic.

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long COVID

B.C. plans to cut payments for long-COVID clinics, leaving patients in lurch

Published July 27, 2025

Published by: Victoria Times Colonist
Published on: July 27, 2025
By Alec Lazenby, Vancouver Sun

A virtual clinic that treats patients for long COVID and other chronic conditions is warning that it may have to partially shut down if the province goes ahead with changes on Sept. 1 that would limit the number of patients who can take part in online group appointments.

The B.C. Centre for Long COVID, ME/CFS & Fibromyalgia, run by internal medicine doctors Ric Arseneau and R. Jane McKay, treats 5,000 patients for a variety of chronic diseases, such as myalgic encephalomyelitis, which causes extreme fatigue, and PoTS, a heart rate condition.

After each patient goes through an initial one-on-one consultation, follow-up appointments can take the form of a virtual group medical visit of up to 12 patients, where either Arseneau or McKay take at least one to two questions per patient, or a group medication visit of up to 50 patients, which allows for presentations on different medications and then takes questions from patients.

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vaccines

New COVID-19 vaccine candidate shows strong protection against multiple variants

Published July 18, 2025

Published by: Centenary Institute
Published on: July 18, 2025

A promising new COVID-19 vaccine candidate developed by researchers at the Centenary Institute and the University of Sydney has shown strong potential to protect against both current and emerging coronavirus variants. By targeting features shared by a range of coronaviruses, the vaccine is designed to offer broader and longer-lasting protection as the virus continues to evolve.

The development comes as Australia faces continued COVID-19 circulation during winter, with new Omicron subvariants such as XBB.1.5 contributing to infections and hospitalisations. To date, there have been over 115,000 COVID-19 cases reported to the Australian Government’s National Notifiable Diseases Surveillance System for 2025.

Published in the scientific journal npj Vaccines, the new study shows that the vaccine candidate, named CoVEXS5, protected mice from multiple coronaviruses, including the highly immune-evasive Omicron XBB.1.5 variant and SARS-CoV-1, a relative of SARS-CoV-2 that was responsible for the 2002–2004 SARS outbreak.

In laboratory tests, CoVEXS5 reduced virus levels in the lungs of infected mice by approximately 99.9% compared to unvaccinated controls, demonstrating a dramatic protective effect.

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cognitive issues

COVID hospitalization linked to cognitive impairment 2 years later

Published July 17, 2025

Published by: CIDRAP
Published on: July 17, 2025
By Stephanie Soucheray

Almost 20% of people who were hospitalized for COVID-19 infections early in the pandemic still had signs of impairment with brain function 2 years after infection, finds a new study in Scientific Reports.

The study population came from Portugal, in a region hit hard by the first wave of the COVID-19 pandemic. Based on hospital admission episodes and SARS-CoV-2 infection status from March 2020 to February 2021, the authors identified four groups: group 1 (101) hospitalized for COVID-19 infections, group 2 (87) hospitalized but uninfected with COVID-19, group 3 (252) infected but not requiring hospitalization, and group 4 (258) uninfected and not hospitalized for any reason.

Cognitive assessments were conducted in two parts 2 years after infection, a general screening using the Montreal Cognitive Assessment and a subsequent neuropsychological assessment conducted by one of four psychologists if the score of the general screening was low. Overall, verbal memory, visual memory, executive functions, language, and information processing speed and attention were evaluated.

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Alberta

Alberta wastewater unlocked key information about COVID-19. Could it help with measles too?

Published July 16, 2025

Published by: CBC News
Published on: July 16, 2025
By Jennifer Lee

As Alberta’s measles outbreaks grow, researchers are now watching the province’s wastewater for the highly contagious virus and hoping to determine if the technology could eventually serve as an early detection tool.

The magnitude of Alberta’s outbreaks and the speed at which cases are climbing has sparked widespread concern. As of midday Tuesday, 1,323 cases had been confirmed since the outbreaks began in March.

Piggybacking off weekly wastewater samples, collected through the provincial COVID-19 surveillance program, the team has designed a test that can identify both the wild type measles virus (indicating actual infection) and vaccine-related shedding in the wastewater.

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vaccines

‘Tremendous uncertainty’ for cancer research as US officials target mRNA vaccines

Published July 12, 2025

Published by: The Guardian
Published on: July 12, 2025
By Melody Schreiber

As US regulators restrict Covid mRNA vaccines and as independent vaccine advisers re-examine the shots, scientists fear that an unlikely target could be next: cancer research.

Messenger RNA, or mRNA, vaccines have shown promise in treating and preventing cancers that have often been difficult to address, such as pancreatic cancer, brain tumors and others.

But groundbreaking research could stall as federal and state officials target mRNA shots, including ending federal funding for bird flu mRNA vaccines, restricting who may receive existing mRNA vaccines and, in some places, proposing laws against the vaccines.

The Trump administration has also implemented unprecedented cuts to cancer research, among other research cuts and widespread layoffs at the National Institutes of Health (NIH).

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vaccines

FDA approves Moderna COVID vaccine for kids under 12 at higher risk

Published July 10, 2025

Published by: CIDRAP
Published on: July 10, 2025
By Jim Wappes

Vaccine maker Moderna announced today that the US Food and Drug Administration (FDA) has granted full approval of its Spikevax (mRNA-1273) COVID vaccine for children 6 months to 11 years old. But, because federal officials in May restricted its recommendations for COVID-19 vaccines to adults 65 and older and to people of all ages who are at increased risk for severe disease, Spikevax will be available only to kids in that age range who are at higher risk.

“COVID-19 continues to pose a significant potential threat to children, especially those with underlying medical conditions. Vaccination can be an important tool for protecting our youngest against severe disease and hospitalization,” said Moderna CEO Stéphane Bancel, MBA, MEng. “We appreciate the FDA’s diligent scientific review and approval of Spikevax for pediatric populations at increased risk for COVID-19 disease.”

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long COVID

Experts call new Canadian Long COVID guidelines “contradictory” and “deeply concerning”

Published July 8, 2025

Published by: The Sick Times
Published on: July 8, 2025
By Simon Spichak

Key points you should know:

The McMaster GRADE Centre and Cochrane Canada developed more than 100 recommendations for Long COVID. However, experts say some of these guidelines could harm people with Long COVID.
Some recommend controversial and scientifically unsupported therapies for the disease: exercise and cognitive behavioral therapy. These treatments mirror harmful and debunked recommendations for myalgic encephalomyelitis. They also contradict major guidelines.
The majority of pediatric guideline developers came from the same children’s hospital that parents say has psychologized their children’s symptoms. And one committee member has an inconsistently disclosed conflict of interest.
Professor emeritus Paul Garner attempted to influence the advisory committee, according to emails obtained through a public information access request.
The organizations provided only one week for public comments on the recommendations. Many people with Long COVID stopped responding because they felt their voices were not being heard.

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vaccines

Medical Societies Sue Kennedy and H.H.S. Over Vaccine Advice

Published July 7, 2025

Published by: The New York Times
Published on: July 7, 2025
By Apoorva Mandavilli

Six leading medical organizations filed a lawsuit on Monday against Robert F. Kennedy Jr., the health secretary, and the federal Department of Health and Human Services, charging that recent decisions limiting access to vaccines were unscientific and harmful to the public.

The suit, filed in federal court in western Massachusetts, seeks to restore Covid vaccines to the list of recommended immunizations for healthy children and pregnant women.

Mr. Kennedy has been on a “decades-long mission” to undermine vaccines and to portray them as more dangerous than the illnesses they are designed to prevent, said Richard H. Hughes IV, a lawyer who teaches vaccine law at George Washington University and is leading the effort.

“The secretary’s intentions are clear,” Mr. Hughes said: “He aims to destroy vaccines.”

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Adults who survived childhood cancer are at increased risk of severe COVID-19, says new study

Photo of a woman who is wearing a white coat and a white mask. She has long blond hair. Photo: Bruce Mars / Unsplash.

research

Adults who survived childhood cancer are at increased risk of severe COVID-19, says new study

Published July 4, 2025

Published by: Medical Xpress
Published on: July 4, 2025
By Karolinska Institutet

People who have survived cancer as children are at higher risk of developing severe COVID-19, even decades after their diagnosis. This is shown by a new study from Karolinska Institutet published in the journal The Lancet Regional Health—Europe.

Thanks to medical advances, more and more children are surviving cancer. However, even long after treatment has ended, health risks may remain. In a new registry study, researchers investigated how adult childhood cancer survivors in Sweden and Denmark were affected by the COVID-19 pandemic.

The study included over 13,000 people who had been diagnosed with cancer before the age of 20 and who were at least 20 years old when the pandemic began. They were compared with both siblings and randomly selected individuals from the population of the same gender and year of birth.

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pandemic response

Public health and Icarus: what history [t]eaches about hubris and mistakes

Published July 2, 2025

Published by: Toronto Star
Published on: July 2, 2025
By Iris Gorfinkel

Icarus had a problem: Desperate to escape from prison, he made wings out of feathers and wax. His father warned him not to fly too close to the sun, but Icarus couldn’t resist the freedom of soaring. His wings melted and he plunged to his death.

Like Icarus, public health is given advanced warning, but struggles between freedom and rules. And as in Greek myths, each failure offers a “moral.”

Here are five examples:

Referring to the pandemic in the past tense

COVID-19 is still spreading in unpredictable waves. Although hospitalizations are currently low, the virus landed over 1,000 Ontarians in hospital and killed nearly 500. New variants keep emerging, including the latest NB. 1.8.1, also known as “Nimbus.” It took just three months to become Canada’s dominant variant. Each time a new variant takes over, it threatens built-up immunity from vaccines and previous infections. Although Nimbus isn’t deadlier than previous variants, there’s no guarantee that future variants won’t cause more severe disease.

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Referring to the pandemic in the past tense