Invalidation of a landmark study on COVID-19 published by a French doctor

“Concerns have been raised” relating to respect for “publication ethics” of the journal’s publisher, and “the appropriate conduct of research involving human participants, as well as concerns raised by three of the authors themselves regarding the article’s methodology and conclusions,” stated Elsevier, the publisher of the scientific journal International Journal of Antimicrobial Agents, in a lengthy note justifying this rare retraction.

The article, signed by 18 authors, notably Philippe Gautret, then a professor at the Marseille IHU, and Didier Raoult, who directed this institute, intended to demonstrate the efficacy of hydroxychloroquine, combined with an antibiotic – azithromycin – against COVID-19.

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When the pandemic hit American soil, the country faced a tragic lack of leadership in President Donald Trump, a man who famously did not bother to read his daily briefs. He also spent a lot of time on Twitter, and not only religiously watched Fox News but took policy cues from it. In the emerging crisis — which happened to coincide with Trump’s reelection campaign gearing up — while scientific experts couldn’t get the ear of the president, social media and right-wing media very much could and did.

Trump, who had promised the pandemic would simply disappear, came to embrace a too-good-to-be-true pandemic “solution” in the form of hydroxychloroquine (HCQ), which had captured the excitement of Silicon Valley — and the attention of Elon Musk on Twitter. Though the repurposing of existing drugs is not inherently a bad idea, Team Trump was not interested in engaging in the scientific process to test for safety and efficacy. And it certainly wasn’t the only time Musk or Trump recklessly took off with an idea because they wanted it to be true.

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Tag: hydroxychloroquine