Press "Enter" to skip to content

Tag: immune dysfunction

As COVID Surges, the High Price of Viral Denial

COVID is surging once again and, if you live in British Columbia, you probably already know someone sick with fever, chills and a sore throat.

As of mid-August, about one in every 19 British Columbians were enduring an infection, with or without symptoms.

Although the media routinely dismisses all COVID infections as an inconsequential nuisance, that’s not what the science says. The virus remains deadlier than the flu and repeated infections can radically change your health.

Comments closed

Long COVID puzzle pieces are falling into place – the picture is unsettling

Since 2020, the condition known as long COVID-19 has become a widespread disability affecting the health and quality of life of millions of people across the globe and costing economies billions of dollars in reduced productivity of employees and an overall drop in the work force.

The intense scientific effort that long COVID sparked has resulted in more than 24,000 scientific publications, making it the most researched health condition in any four years of recorded human history.

Long COVID is a term that describes the constellation of long-term health effects caused by infection with the SARS-CoV-2 virus. These range from persistent respiratory symptoms, such as shortness of breath, to debilitating fatigue or brain fog that limits people’s ability to work, and conditions such as heart failure and diabetes, which are known to last a lifetime.

Comments closed

‘Visionary’ study finds inflammation, evidence of Covid virus years after infection

Remember when we thought Covid was a two-week illness? So does Michael Peluso, assistant professor of medicine at the University of California, San Francisco.

He recalls the rush to study acute Covid infection, and the crush of resulting papers. But Peluso, an HIV researcher, knew what his team excelled at: following people over the long term.

So they adapted their HIV research infrastructure to study Covid patients. The LIINC program, short for “Long-term Impact of Infection with Novel Coronavirus,” started in San Francisco at the very beginning of the pandemic. By April 2020, the team was already seeing patients come in with lingering illness and effects of Covid — in those early days still unnamed and unpublicized as long Covid. They planned to follow people’s progress for three months after they were infected with the virus.

Comments closed

A new look at why old age is linked to severe, even fatal COVID

A longstanding question has nagged the COVID battle for more than four years: Why does the infection cause severe disease in older people? The question has remained despite a global cadre of medical investigators having produced some of the reasons—but not the entire story.

Ever since the beginning of the pandemic in 2020, it has been abundantly clear that older adults are at substantial risk of severe, even fatal COVID. Yet, the underlying mechanisms for their susceptibility were not always clear despite studies that took co-morbidities into account, like diabetes, heart and lung disorders, and other chronic vagaries of age that can worsen a bout with an infectious disease.

To date, scientists have blamed a dysregulated immune system, an age-related affinity toward excessive blood clotting, and an overall decline in the key soldiers of the adaptive immune system, T and B cells, to explain increased risks for severe COVID in the aging population. And while all of those factors may play a role, an inevitable question looms large: Why?

Comments closed

Shingles cases are increasing in New South Wales. Experts say COVID might be why

I think that GPs would all agree that we’ve probably seen more cases of shingles over the last period of time over COVID. Absolutely, shingles is an illness that, theoretically and I think in practical reality, has been increased through COVID-19.

Comments closed

“They’re Taking Away Your Right To Be Healthy.”

The tide is turning. Thanks to all the people making noise on social media and bugging their families, while continuing to wear masks and build air purifiers no matter what anyone says, there’s a trace of hope.

—Jessica Wildfire
Comments closed

It’s not the quarantine that made so many other diseases surge: It’s the COVID

The world is nearly four years into the COVID-19 pandemic, but how the SARS-CoV-2 virus damages human lives, both in the short term and across a span of years, is still becoming clear. Earlier this month, a study in Lancet showed that 54% of those infected in the first months of the pandemic were still experiencing symptoms over three years later.

Comments closed

Covid may have permanently damaged people’s immunity

Covid infections are putting people at higher risk of diabetes, strokes, heart disease and other long-term illnesses – but experts warn it may be decades before the full impact is known.

Comments closed

Long COVID: The hunt for causes and cures

Hannah Davis misses her old self. Like so many people around the world, she has seen her life upended by long COVID, which has made many once-routine activities impossible. The 32-year-old has stopped working at her job in the field of machine learning and generative models. It’s too cognitively taxing; the lights from display monitors are disorienting. Merely standing up from a sitting position causes her heart rate to shoot to 170 beats per minute, the equivalent of doing a good jog.

Comments closed

Are repeat COVID infections dangerous? What the science says

Nature

April 26, 2023

“People with repeat infections were twice as likely to die and three times as likely to be hospitalized, have heart problems or experience blood clots than were people who were infected only once. In a surprising twist, vaccination status didn’t seem to have an impact — although other studies show vaccines to be protective. Whether these results hold true for the general population is up for debate. The Veterans Affairs cohort was made up mostly of older white men, which is not representative of the wider population.”

Comments closed

Immune systems seriously weakened by COVID

Emergency wards remain busy two years after the first COVID-19 vaccines arrived in Ontario in part because the virus depletes the body’s supply of T-cells, leaving young and old alike vulnerable to secondary infections, says a University of Waterloo immunologist.

T-cells are the front-line soldiers of the immune system, and the number of T-cells typically increases when the body is fighting off an infection, said Barb Katzenback, who studies viruses.

“Individuals who are infected with COVID have many fewer T-cells,” said Katzenback. “That’s a problem for us because T-cells are a really important part of our immune system that helps defend us against infection.”

Comments closed

Opinion: We don’t know what’s causing the tsunami of sick kids, but we’d better figure it out fast

Something concerning is happening to our children. Unlike previous autumns, this year there seem to be far more kids falling ill, and far too many…

Comments closed

Video | Is COVID-19 Dysregulating Our Immune Systems?

Are people becoming sick more often, experiencing more severe symptoms and having more difficulty treating viral infections after having had COVID-19? If so, why? Epidemiologists,…

Comments closed