A single-center study conducted at a free community testing site in Maryland suggests that patient-administered BinaxNow COVID-19 rapid antigen tests (RATs) have similar accuracy as those performed by a clinician, although the results can be misinterpreted or falsely negative.

Researchers from the Baltimore Convention Center Field Hospital and Johns Hopkins University and their collaborators compared the sensitivity and specificity of Abbott’s BinaxNOW home RAT with those administered by a healthcare provider and reverse transcription-polymerase chain reaction (RT-PCR) from February to July 2022, a period of Omicron variant predominance.

The median age of the 953 participants was 34 years, 60.6% were women, 58.6% were White, 98.2% were English-speaking, and 34.1% had at least one COVID-19 symptom. Hospital staff administered both a RAT and an RT-PCR test to participants, who then self-tested with a RAT, the results of which were both self-reported and reviewed by the researchers.