Researchers from Helmholtz Munich and Ludwig-Maximilians-Universität (LMU) have identified a mechanism that may explain the neurological symptoms of Long COVID. The study shows that the SARS-CoV-2 spike protein remains in the brain’s protective layers, the meninges, and the skull’s bone marrow for up to four years after infection. This persistent presence of the spike protein could trigger chronic inflammation in affected individuals and increase the risk of neurodegenerative diseases. The team, led by Prof. Ali Ertürk, Director at the Institute for Intelligent Biotechnologies at Helmholtz Munich, also found that mRNA COVID-19 vaccines significantly reduce the accumulation of the spike protein in the brain. However, the persistence of spike protein after infection in the skull and meninges offers a target for new therapeutic strategies.
Comments closedTag: long COVID
Stanford Doctor Tapped for Key Post by Trump Advocated for Letting COVID Spread
President-elect Donald Trump’s choice this week to lead the National Institutes of Health is a controversial Stanford researcher who was highly critical of the COVID-19 pandemic response, drawing pushback from the medical community and some still suffering from the long-term effects of the disease.
Dr. Jay Bhattacharya, a professor of health policy and senior fellow at the Stanford Institute for Economic Policy Research, was one of three co-authors of a 2020 letter that challenged policies like lockdowns and mask mandates, and called for speeding up herd immunity.
Comments closedAnalysis of 25 studies shows reduced risk of long COVID after vaccination
A new meta-analysis of studies involving more than 14 million people published in the Journal of Infection shows that COVID-19 vaccination is associated with a lower risk of developing long COVID, with two doses reducing the odds by 24% and one dose reducing the odds by 15%.
In the 25 studies published up to February 2024 that were included for analysis, long COVID was defined as persistent symptoms at 3 months or beyond, and all studies compared long-COVID symptoms between vaccinated and unvaccinated groups, with the number of doses received by participants specified. All studies included were observational trials and included in total 14,128,260 participants.
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Everything Wrong with Canada’s Proposed Long COVID Recommendations
Researchers involved in the organizations Cochrane Canada and the McMaster GRADE Centre at McMaster University are developing guidelines to prevent and treat Long COVID in Canada. Their effort is supported by the Public Health Agency of Canada and their recommendations would likely have major sway in the way Long COVID is treated if adopted.
Every month, they release new recommendations and provide an opportunity for public comment. On November 20th, the group released a new set of Canadian Post-COVID Condition (CAN-PCC) recommendations which propose harmful and ineffective treatments: Exercise to prevent Long COVID and cognitive behavioral therapy (CBT) to treat post-exertional malaise (PEM).
Comments closedThe story of Alberta’s rural long COVID program that never was
As better diagnosis and symptom management emerged for people with long COVID, researchers in Alberta set to work creating a program that could remotely connect urban specialists and rural patients. Between development and clinical implementation, the project was shelved.
With the province closing its clinics dedicated to treating people with long COVID, the story of Alberta’s innovative rural outreach program appears destined to remain incomplete.
Long COVID, or post COVID syndrome, refers to patients who are still experiencing symptoms twelve weeks after the initial infection. According to Health Canada, the condition affects about 1 in 9 adults who have had COVID.
Comments closedLong Covid could cost the economy billions every year
Working days lost to long Covid could be costing the economy billions of pounds every year as patients struggle to cope with symptoms and return to work, finds a new study led by UCL researchers.
Comments closedDifficulty in accessing care for healthcare workers who have contracted long COVID
While on the front line at the height of the COVID-19 health crisis, many healthcare workers are struggling to access care after contracting long COVID. Only 12% of healthcare workers who suffer from it have received rehabilitation care, according to a research report by the Institut national de santé publique du Québec (INSPQ).
Comments closedAbout 2,000 patients are on the long COVID clinic waiting list
(Montreal) The rehabilitation process is long for patients with long COVID, which can limit professionals in their acceptance of new patients. This issue, added to the other ills of the healthcare system, means that some 4,000 patients end up in the network of long COVID clinics, half of whom are on the waiting list.
Comments closedThe risk of long COVID reaches 37% after three infections, according to the INSPQ
As COVID-19 continues to circulate widely, a report from the INSPQ warns that the risk of getting long COVID increases with each reinfection, and notes that the Quebec health system is failing to help the growing number of people who have had persistent symptoms for months or even years.
The report by the Institut national de la santé publique du Québec (INSPQ), which surveyed thousands of health workers in Quebec who were infected between the beginning of the pandemic and summer 2023, was released quietly on Monday. Yet, this report warns that post COVID-19 condition, commonly known as long COVID, is affecting more and more people.
« This is an important and real issue. We want to raise awareness among the public and public health authorities,” says Sara Carazo, one of the authors of the report.
Comments closed‘Long COVID has really mystified’: Western University researchers take steps to unravel long COVID mysteries
Long COVID can have wide-ranging impacts, but is most commonly associated with brain fog, breathing difficulties and debilitating fatigue.
“Long COVID has really mystified a lot of physicians and scientists,” according to Dr. Douglas Fraser. Fraser is a researcher with Western University’s Schulich School of Medicine and Dentistry, based in London, Ont.
Comments closedPaxlovid tied to fewer COVID-19 hospitalizations, reduced risk of long COVID
A new retrospective cohort study conducted in Dubai shows that the antiviral nirmatrelvir plus ritonavir, sold as Paxlovid, is tied to a 61% reduction in COVID-19 hospitalization and a 58% lower rate of long COVID.
Comments closed‘Do no harm’ is hurting 400 million long Covid patients worldwide
Imagine, for a moment, that you wake up one morning with a debilitating illness that won’t let go. Weeks and months pass, but the crushing fatigue, constant headaches, and aching muscles remain. You can’t think straight. Simply showering or doing the dishes leaves you floored for days at a time, and the unpredictable symptoms — shortness of breath, dizziness, a racing heart — ebb and flow without warning. You find your life as you knew it slipping away.
This is life with long Covid: a condition that transforms the familiar rhythms of daily life into a living nightmare and constant battle for energy and clarity. But what happens when the only hope of lessening its severity becomes an issue of equity?
We are two of the more than 400 million people worldwide who have experienced long Covid. While we are both over four years into this illness, there is still not a single FDA-approved treatment for this devastating condition. Given the slow pace of research and development, there is unlikely to be proven treatment for years — possibly decades.
Comments closedLong COVID patients suffer high rate of autonomic disorders, researchers say
Medical researchers at the University of Calgary say a condition affecting autonomic bodily processes — those that occur automatically, such as heart rate, bladder function and sweating — is frequently found in people diagnosed with long COVID.
The condition is known as dysautonomia, an umbrella term for a group of related conditions. Support networks for those who suffer from it are working to raise awareness throughout October, which has been deemed Dysautonomia Awareness Month by the advocacy group, Dysautonomia International.
Comments closedSince the COVID pandemic began, claims that the disease poses only minimal risk to children have spread widely, on the presumption that the lower rate of severe acute illness in kids tells the whole story. Notions that children are nearly immune to COVID and don’t need to be vaccinated have pervaded.
These ideas are wrong. People making such claims ignore the accumulating risk of long COVID, the constellation of long-term health effects caused by infection, in children who may get infected once or twice a year. The condition may already have affected nearly six million kids in the U.S. Children need us to wake up to this serious threat. If we do, we can help our kids with a few straightforward and effective measures.
Comments closedUltra-powered MRI scans show damage to brain’s ‘control centre’ is behind long-lasting Covid-19 symptoms
Damage to the brainstem – the brain’s ‘control centre’ – is behind long-lasting physical and psychiatric effects of severe Covid-19 infection, a study suggests.
Using ultra-high-resolution scanners that can see the living brain in fine detail, researchers from the Universities of Cambridge and Oxford were able to observe the damaging effects Covid-19 can have on the brain.
The study team scanned the brains of 30 people who had been admitted to hospital with severe Covid-19 early in the pandemic, before vaccines were available. The researchers found that Covid-19 infection damages the region of the brainstem associated with breathlessness, fatigue and anxiety.
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