Press "Enter" to skip to content

Tag: research

Study: 6% of US adults have long COVID, and many have reduced quality of life

Two new studies paint a comprehensive picture of current long COVID cases in the United States, and both suggest the condition limits daily activities for a significant proportion of those affected.

Comments closed

America’s Public Health Breakdown Is Just Getting Started

The United States has a health-care system that is terrible and getting worse. It also has a health science system that is the best in the world and about to be dismantled.

The impending return of Donald Trump to the White House seems likely to collapse American health science, with consequences as disastrous for the rest of the world as for the approximately 340 million Americans in the U.S. Canada may be able to soften the impact here, but it will not be easy.

Comments closed

Invalidation of a landmark study on COVID-19 published by a French doctor

“Concerns have been raised” relating to respect for “publication ethics” of the journal’s publisher, and “the appropriate conduct of research involving human participants, as well as concerns raised by three of the authors themselves regarding the article’s methodology and conclusions,” stated Elsevier, the publisher of the scientific journal International Journal of Antimicrobial Agents, in a lengthy note justifying this rare retraction.

The article, signed by 18 authors, notably Philippe Gautret, then a professor at the Marseille IHU, and Didier Raoult, who directed this institute, intended to demonstrate the efficacy of hydroxychloroquine, combined with an antibiotic – azithromycin – against COVID-19.

Comments closed

COVID-19 linked to more heart complications than flu, RSV

A new study published in BMC Cardiovascular Disorders shows that pediatric and young adult COVID-19 patients are more at risk for cardiac complications than flu or RSV patients of the same age.

The study was based on hospitalized US patients from 2020 through 2021 tracked through the National Inpatient Sample. In total 212,655 respiratory virus admissions were recorded, including 85,055 from COVID-19, 103,185 from RSV, and 24,415 from influenza.

Comments closed

Guelph wastewater testing will continue for COVID-19 and more by university researchers

Wastewater in Guelph will continue to be monitored for COVID-19, influenza and other illnesses through a new partnership between researchers at the University of Guelph and Wellington-Dufferin-Guelph Public Health.

The researchers will get samples of wastewater three times a week, then will submit their findings to public health, which will in turn publish it to a public online dashboard.

Provincial funding for wastewater testing was cut on July 31 with the Ontario government citing a federal program that tests wastewater; however, none of the testing sites are in Waterloo region or Guelph.

Comments closed

New imaging shows virus invading the body and lingering for years, potentially explaining Long COVID

Next time you think of dismissing COVID as just another annoying common cold it may pay to visualise what you see so starkly in this paper, the virus moving freely around your body and finding a long-term home in all sorts of places where it can really cause trouble, including the brain and the heart.

This work further emphasises the need for individuals, and societies as a whole to take this infection more seriously and try and reduce the amount of transmission using the tools we currently have, most especially vaccination, clean indoor air approaches and well-fitted masks in crowded and poorly ventilated indoor settings.

— Professor Brendan Crabb, director and CEO of the Macfarlane Burnet Institute for Medical Research and Public Health
Comments closed

Why hasn’t the bird flu pandemic started?

If the world finds itself amid a flu pandemic in a few months, it won’t be a big surprise. Birds have been spreading a new clade of the H5N1 avian influenza virus, 2.3.4.4b, around the world since 2021. That virus spilled over to cattle in Texas about a year ago and spread to hundreds of farms across the United States since. There have been dozens of human infections in North America. And in some of those cases the virus has shown exactly the kinds of mutations known to make it better suited to infect human cells and replicate in them.

No clear human-to-human transmission of H5N1 has been documented yet, but “this feels the closest to an H5 pandemic that I’ve seen,” says Louise Moncla, a virologist at the University of Pennsylvania. “If H5 is ever going to be a pandemic, it’s going to be now,” adds Seema Lakdawala, a flu researcher at Emory University.

Comments closed

Single bird flu mutation could let it latch easily to human cells, study finds

Scientists from the Scripps Research Institute are reporting that it would take just a single mutation in the version of bird flu that has swept through U.S. dairy herds to produce a virus adept at latching on to human cells, a much simpler step than previously imagined.

To date, there have been no documented cases of one human passing avian influenza to another, the Scripps scientists wrote in their paper, which was published Thursday in the journal Science. The mutation they identified would allow the virus to attach to our cells by hitching itself to a protein on their surface, known as the receptor.

Comments closed

Mistrustful adults could be more vulnerable to vaccine conspiracy theories and bad at spotting fake news, report finds

Because outrage is associated with increased engagement online, outrage evoking misinformation may be likely to spread farther in part because of the algorithmic amplification of engaging content.

This is important because algorithms may up-rank news articles associated with outrage, even if a user intended to express outrage toward the article for containing misinformation.

Our findings suggest that misinformation exploits outrage to spread and offers concrete evidence for policy-makers to consider when attempting to craft effective solutions.

Comments closed

Almost a third of preteens, teens with long COVID still not recovered at 2 years, study shows

A new study from UK investigators shows that — while most COVID-19 patients ages 11 to 17 who reported long-COVID symptoms 3 months after the initial infection no longer experienced lingering symptoms at 2 years — 29% still did.

The findings, published in the journal Communications Medicine, come from the National Long COVID in Children and Young People cohort study, which followed up on thousands of young people after their COVID-19 diagnoses.

Comments closed

Experimental study shows connection between COVID infection and age-related blindness

An experimental study in mice shows that SARS-CoV-2 infection can damage the retinas, with long-term implications for vision. Post-acute sequelae of SARS-CoV-2 infection include various neurocognitive symptoms, suggesting the virus can affect the central nervous system. The eyes are also part of the central nervous system, but little is known about the virus’s effects on these organs.

Comments closed

Severe COVID-19 may be a risk factor for multiple sclerosis

COVID-19 may be a risk factor for multiple sclerosis (MS). This has been shown by new research at Örebro University and Örebro University Hospital, Sweden. The study is published in the journal Brain Communications.

“We saw a raised risk of MS among people who had severe COVID-19. However, only an extremely small number of people who had severe COVID-19 received a subsequent MS diagnosis,” says Scott Montgomery, professor in clinical epidemiology.

Comments closed

Long a ‘Crown Jewel’ of Government, N.I.H. Is Now a Target

The National Institutes of Health, the world’s leading public funder of biomedical research, has an enviable track record. Research supported by the agency has led to more than 100 Nobel Prizes and has supported more than 99 percent of the drugs approved by federal regulators from 2010 to 2019.

No surprise, then, that the agency has been called “the crown jewel of the federal government.” But come January, when President-elect Donald J. Trump and congressional Republicans take charge, the N.I.H. may face a reckoning.

Comments closed

Long COVID: SARS-CoV-2 Spike Protein Accumulation Linked to Long-Lasting Brain Effects

Researchers from Helmholtz Munich and Ludwig-Maximilians-Universität (LMU) have identified a mechanism that may explain the neurological symptoms of Long COVID. The study shows that the SARS-CoV-2 spike protein remains in the brain’s protective layers, the meninges, and the skull’s bone marrow for up to four years after infection. This persistent presence of the spike protein could trigger chronic inflammation in affected individuals and increase the risk of neurodegenerative diseases. The team, led by Prof. Ali Ertürk, Director at the Institute for Intelligent Biotechnologies at Helmholtz Munich, also found that mRNA COVID-19 vaccines significantly reduce the accumulation of the spike protein in the brain. However, the persistence of spike protein after infection in the skull and meninges offers a target for new therapeutic strategies.

Comments closed

Stanford Doctor Tapped for Key Post by Trump Advocated for Letting COVID Spread

President-elect Donald Trump’s choice this week to lead the National Institutes of Health is a controversial Stanford researcher who was highly critical of the COVID-19 pandemic response, drawing pushback from the medical community and some still suffering from the long-term effects of the disease.

Dr. Jay Bhattacharya, a professor of health policy and senior fellow at the Stanford Institute for Economic Policy Research, was one of three co-authors of a 2020 letter that challenged policies like lockdowns and mask mandates, and called for speeding up herd immunity.

Comments closed

Analysis of 25 studies shows reduced risk of long COVID after vaccination

A new meta-analysis of studies involving more than 14 million people published in the Journal of Infection shows that COVID-19 vaccination is associated with a lower risk of developing long COVID, with two doses reducing the odds by 24% and one dose reducing the odds by 15%.

In the 25 studies published up to February 2024 that were included for analysis, long COVID was defined as persistent symptoms at 3 months or beyond, and all studies compared long-COVID symptoms between vaccinated and unvaccinated groups, with the number of doses received by participants specified. All studies included were observational trials and included in total 14,128,260 participants.

Comments closed

Covid Can Raise the Risk of Heart Problems for Years

Since nearly the start of the pandemic, scientists have known that a Covid-19 infection increases the risk of heart problems. A growing body of research now suggests that this risk can last until well after the infection has cleared.

One recent study, conducted by researchers at the University of Southern California and Cleveland Clinic, found that a Covid-19 infection doubled the risk of a major cardiovascular event for up to three years afterward. What’s more, the study found that infections severe enough to require hospitalization increased the likelihood of cardiac events as much as — or more than — having previously had a heart attack did.

Comments closed

Like ‘old Twitter’: The scientific community finds a new home on Bluesky

In July 2023, Adam Kucharski asked his Twitter followers: What platform do you think you will be spending the most time on a year from now? Like many scientists on Twitter, Kucharski, a mathematical modeler of infectious diseases, was increasingly frustrated with changes to the platform since Elon Musk bought it in October 2022. But of the more than 1300 people who responded to his poll, the vast majority expected to keep posting on Twitter, which was renamed X just 2 weeks later. About one-quarter were banking on Threads, Meta’s Twitter rival. Only about 7% chose Bluesky.

Now, that has changed, in a big way. Although academics mostly stuck with X in the year after the poll, Bluesky has rapidly emerged as the new online gathering place for researchers, Kucharski among them. They are drawn by its Twitter-like feel, welcoming features, and, increasingly, the critical mass of scientists in many fields who have already made the move. “The majority has spoken, and researchers are moving en masse” to Bluesky, says De-Shaine Murray, a neuroscientist at Yale University who has also migrated to Bluesky.

Comments closed