Press "Enter" to skip to content

Tag: research

Six Nobel laureates speak out against Trump: ‘The closest analogy is with the Hitler regime’

In recent weeks, EL PAÍS contacted most of the Nobel Prize winners in Physics, Chemistry, and Medicine from the United States over the past 20 years with a questionnaire about Donald Trump’s policies on science, research, and health. The vast majority are established researchers — some even retired — who should not fear retaliation; but only a handful of them agreed to respond.

“Why am I sad?” writes Roald Hoffmann, winner of the 1981 Nobel Prize in Chemistry. “We came to the U.S. when I was 11. Even as my parents could not work making full use of their training and talents, the country gave their child, me (and my sister, born here), a chance to get an education and to do wonderful research with talented coworkers from all over the world. If the Trump policies are carried through, the full flow of what I experienced will be very unlikely in the generation of my scientific grandchildren.”

Comments closed

Kennedy Sought to Fire C.D.C. Director Over Vaccine Policy

Health Secretary Robert F. Kennedy Jr. summoned Susan Monarez, the director of the Centers for Disease Control and Prevention, to his office in Washington earlier this week to deliver an ultimatum.

She needed to fire career agency officials and commit to backing his advisers if they recommended restricting access to proven vaccines — or risk being fired herself, according to people familiar with the events.

Dr. Monarez’s refusal to do so led to an extraordinary standoff on Thursday that paralyzed the nation’s health agency, which is still reeling from mass layoffs and a shooting this month that killed a police officer and terrified employees.

Comments closed

CDC director fired after she ‘refused to rubber-stamp’ Kennedy’s vaccine directives

Susan Monarez, PhD, was fired late yesterday as director of the Centers for Disease Control and Prevention (CDC) after clashing with Health and Human Services (HHS) Secretary Robert F. Kennedy Jr. on vaccine policy.

The White House fired her after Monarez refused to resign, and the action kicked off a mass resignation wave of three of the CDC’s top officials: Debra Houry, MD, MPH, the CDC’s chief medical officer; Demetre Daskalakis, MD, MPH, head of the CDC’s National Center for Immunization and Respiratory Diseases; and Daniel Jernigan, MD, MPH, head of the CDC’s National Center for Emerging and Zoonotic Infectious Diseases. Earlier this week Jennifer Layden, MD, PhD, who led the Office of Public Health Data, also stepped down.

Comments closed

Wildfires are reversing Canada’s progress on improving air quality

It’s hard not to forget the 2023 Canadian wildfire season, when more than 16 million hectares of forest were lost, thousands were displaced and smoke suffocated cities across both Canada and the U.S.

And it turns out Canada experienced its worst air pollution levels that year since 1998, according to a new report released today by the University of Chicago’s Air Quality Life Index (AQLI). At the same time, the report found that pollution levels didn’t change much for the rest of the world in 2023.

If those levels continued for a person’s lifetime, the average Canadian would lose roughly two years of their life expectancy, according to the report.

Efforts have been made around the world, including in Canada, to curb harmful emissions of fine particulate matter with a diameter of less than 2.5 micrometres, also known as PM 2.5. But wildfires are reversing those advances — with serious health consequences.

Comments closed

Wildfire smoke far more dangerous to health than thought, say scientists

Choking smoke spewed by wildfires is far more dangerous than previously thought, a new study has found, with death tolls from short-term exposure to fine particulates underestimated by 93%.

Researchers found that 535 people in Europe died on average each year between 2004 and 2022 as a result of breathing in the tiny toxic particles known as PM2.5 that are released when wildfires rage.

Under standard methods, which assume PM2.5 from wildfires is as deadly as from other sources, such as traffic, they would have expected just 38 deaths a year.

Comments closed

Do you have long COVID? Here’s how to tell, and what we know about the condition so far

It has been more than five years since the dawn of the COVID-19 pandemic, yet innumerable Canadians are still living with the consequences months or even years after their initial infection.

Much remains unknown about long COVID, or Post COVID Condition (PCC), despite the ailment affecting millions of Canadians and leaving thousands out of work. But as research continues to develop, scientists have gleaned some pieces of the puzzle.

Here’s what we know so far about what long COVID is, why it happens and how to tell if you have it.

Comments closed

‘Distracting the public’: group of health professionals call for RFK Jr to be removed

A grassroots organization of health professionals have released a report outlining major health challenges in the US and calling for the removal of Robert F Kennedy Jr from the US Department of Health and Human Services (HHS).

The report from Defend Public Health, a new organization of about 3,000 health professionals and allies, is an attempt to get ahead of misinformation and lack of information from health officials.

In an effort to keep making progress in public health, Defend Public Health’s report was slated to coincide with that of the anticipated second US report to “make America healthy again” (Maha). The first Maha report was released in May, and a second report was expected this week – but amid turmoil at the health agencies, it has reportedly been delayed for several weeks.

Comments closed

Lab-made sugar-coated particle blocks Covid-19 infection — Possible new treatment on the horizon

Groundbreaking research led by a Swansea University academic has revealed a synthetic glycosystem — a sugar-coated polymer nanoparticle — that can block Covid-19 from infecting human cells, reducing infection rates by nearly 99%.

The glycosystem is a specially designed particle that mimics natural sugars found on human cells. These sugars, known as polysialosides, are made of repeating units of sialic acid — structures that viruses often target to begin infection. By copying this structure, the synthetic molecule acts as a decoy, binding to the virus’s spike protein and preventing it from attaching to real cells.

Unlike vaccines, which trigger immune responses, this molecule acts as a physical shield, offering a novel approach to infection prevention.

Comments closed

HHS scraps further work on life-saving mRNA vaccine platform

In what experts say will hobble pandemic preparedness, US Health and Human Services (HHS) Secretary Robert F. Kennedy Jr. yesterday announced the dismantling of the country’s mRNA vaccine-development programs—the same innovation that allowed rapid scale-up of COVID-19 vaccines during the public health emergency.

The Biomedical Advanced Research and Development Authority (BARDA) is terminating 22 mRNA vaccine-development contracts totaling just under $500 million, including an award to Moderna/University of Texas Medical Branch for a vaccine against the H5N1 avian flu now sweeping the world. That grant was terminated in late May.

Contracts awarded to Emory University and Tiba Biotech were cancelled, and agreements with Luminary Labs, ModeX, and Seqirus have been scaled back.

Comments closed

What’s all this wildfire smoke doing to your health? Here’s what experts have to say

People who breathe air polluted with large amounts of wildfire smoke visit hospital emergency rooms more often for respiratory symptoms, according to a Canadian emergency room physician and chair of the Global Climate and Health Alliance.

Rates of heart attack and cardiac arrest also increase after a couple of days of exposure, Dr. Courtney Howard said.

“So don’t just attribute that feeling of heaviness in your chest to asthma,” said Howard, who works in Yellowknife and is president of the Northwest Territories Medical Association.

“If you have other risk factors for cardiovascular disease especially, go see your friendly local emergency department.”

Comments closed

RFK Jr. pulls $500 million in funding for vaccine development

WASHINGTON (AP) — The Department of Health and Human Services will cancel contracts and pull funding for some vaccines that are being developed to fight respiratory viruses like COVID-19 and the flu.

Robert F. Kennedy Jr. announced in a statement Tuesday that 22 projects, totaling $500 million, to develop vaccines using mRNA technology will be halted.

Kennedy’s decision to terminate the projects is the latest in a string of decisions that have put the longtime vaccine critic’s doubts about shots into full effect at the nation’s health department. Kennedy has pulled back recommendations around the COVID-19 shots, fired the panel that makes vaccine recommendations, and refused to offer a vigorous endorsement of vaccinations as a measles outbreak worsened.

Comments closed

Bird Flu May Be Airborne on Dairy Farms, Scientists Report

The bird flu virus that has beset dairy farms since early last year may be spreading through the air in so-called milking parlors and through contaminated wastewater, as well as from milking equipment, scientists have found.

The Department of Agriculture has said that the virus spreads primarily from milking equipment or is carried by dairy workers and vehicles traveling between farms.

But in the new study, scientists found live virus in the air of milking facilities, suggesting that cows and farmworkers might have become infected by inhaling the pathogen. The virus may also spread by water used to clean cattle barns or contaminated with discarded milk.

Comments closed

Analysis: 2024-25 COVID vaccines offered strong protection against worst outcomes in seniors

The 2024-25 COVID mRNA vaccines targeting JN.1 were highly effective in protecting against hospitalization and death for at least 4 months in a cohort of Danish citizens aged 65 and older by October 1, 2024. The new analysis estimating the vaccine efficacy (VE) of last season’s COVID vaccines was published earlier this week in The Lancet Infectious Diseases.

In total, 894,560 Danish residents were included in the study, with a median age of 76. By Jan 31, 2025, 820,229 (91.7%) of the participants had received a JN.1 vaccine. Among those without updated JN.1 vaccination (74,331), 278 COVID-19 hospitalizations and 84 deaths were observed during 25.6 million person-days.

Comments closed

Biological causes of long COVID discovered: the virus persists for months in the brain

Long COVID, often attributed to a psychosomatic mechanism, has biological causes, a study reveals. Months after the infection, the virus was still active, at low levels, in the brainstem of hamsters.

“We hope to bring relief to the patients who may have heard that they are not sick, that it is ‘in their heads.’ What we are showing in the laboratory is that long COVID has a biological cause!,” says Guilherme Dias de Melo, a veterinarian and researcher in infectious diseases and neuropathologies at the Institut Pasteur. Eighty days after the initial infection, the COVID-19 virus was found, still infectious, in the brainstems of hamsters affected by symptoms similar to those of long COVID, according to the work that he has directed and published in the journal Nature Communications.

Comments closed

COVID infection early in pandemic linked to higher risk of cancer death, CU study finds

Cancer survivors infected with COVID-19 in the early months of the pandemic had a higher risk of dying from dormant cells reawakening, Colorado researchers found, though they don’t know whether people who get the virus now face the same risk.

Experiments in mice found that genetically modified animals were more likely to have signs of metastatic cancer in their lungs if infected with flu or COVID-19 than engineered mice that researchers didn’t give a virus, said James DeGregori, deputy director of the University of Colorado Cancer Center in Aurora.

That finding launched an international partnership to determine whether the same thing happened in people, he said.

Comments closed

‘Sleeping’ cancer cells in the lungs can be roused by COVID and flu

Hidden in the lungs of some breast cancer survivors are tumour cells that can remain dormant for decades — until they one day trigger a relapse. Now, experiments in mice show that these rogue cells can be roused from their slumber by common respiratory illnesses such as COVID-19 or the flu.

The findings, published in Nature on 30 July1, seem to extend to humans too: data from thousands of people show that infection with the coronavirus SARS-CoV-2 is linked with a nearly twofold increase in cancer-related death, possibly helping to explain why cancer death rates increased early during the COVID-19 pandemic.

Comments closed

New COVID-19 vaccine candidate shows strong protection against multiple variants

A promising new COVID-19 vaccine candidate developed by researchers at the Centenary Institute and the University of Sydney has shown strong potential to protect against both current and emerging coronavirus variants. By targeting features shared by a range of coronaviruses, the vaccine is designed to offer broader and longer-lasting protection as the virus continues to evolve.

The development comes as Australia faces continued COVID-19 circulation during winter, with new Omicron subvariants such as XBB.1.5 contributing to infections and hospitalisations. To date, there have been over 115,000 COVID-19 cases reported to the Australian Government’s National Notifiable Diseases Surveillance System for 2025.

Published in the scientific journal npj Vaccines, the new study shows that the vaccine candidate, named CoVEXS5, protected mice from multiple coronaviruses, including the highly immune-evasive Omicron XBB.1.5 variant and SARS-CoV-1, a relative of SARS-CoV-2 that was responsible for the 2002–2004 SARS outbreak.

In laboratory tests, CoVEXS5 reduced virus levels in the lungs of infected mice by approximately 99.9% compared to unvaccinated controls, demonstrating a dramatic protective effect.

Comments closed