Tag: research

Published by: Folio - University of Alberta
Published on: November 7, 2025
By Gillian Rutherford

Research published today in Cell Reports Medicine reveals key biological differences that may explain why women with long COVID — especially those who develop chronic fatigue syndrome — tend to experience more severe and persistent symptoms than men do.

Post COVID-19 condition, or long COVID, is diagnosed when neurological, respiratory or gastrointestinal symptoms develop or continue three months or more after an acute SARS-CoV-2 infection.

The likelihood of developing long COVID is three times higher for women than men, but until now the underlying biological mechanisms driving this disparity have remained unknown.

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vaccines

Risk of rare heart complications in children higher after COVID-19 infection than after vaccination

Published November 4, 2025

Published by: University of Cambridge
Published on: November 4, 2025

Children and young people faced long-lasting and higher risks of rare heart and inflammatory complications after COVID-19 infection, compared to before or without an infection, according to new research. Meanwhile COVID-19 vaccination was only linked to a short-term higher risk of myocarditis and pericarditis.

The study is the largest of its kind in this population, and is published today in The Lancet Child and Adolescent Health. It was led by scientists at the Universities of Cambridge and Edinburgh, and University College London, with support from the British Heart Foundation (BHF) Data Science Centre at Health Data Research UK.

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long COVID

COVID vaccination cuts risk of long-term symptoms in teens by over a third, data suggest

Published November 3, 2025

Published by: CIDRAP
Published on: November 3, 2025
By Mary Van Beusekom

The risk of long COVID was 36% lower in adolescents vaccinated within 6 months before their first infection than in their unvaccinated peers, suggests an analysis of US Researching COVID to Enhance Recovery (RECOVER) trial data published late last week in Vaccine.

The study, led by Massachusetts General Hospital researchers, involved 724 adolescents aged 12 to 17 years who were vaccinated against COVID-19 within the previous 6 months and 507 unvaccinated youth matched on sex, symptom onset, and enrollment date.

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cardiovascular disease

Covid and Flu Can Triple Your Risk of Heart Attack

Published October 29, 2025

Published by: The New York Times
Published on: October 29, 2025
By Nina Agrawal

The risk of a heart attack triples within the first few weeks after a Covid-19 infection, the study suggested, and quadruples in the month after a flu infection. The study, published Wednesday in the Journal of the American Heart Association, was a large review and analysis of existing research.

“It endorses a general idea that we’ve been thinking about and talking about for the past several years — that infections are generally not benign,” said Dr. Ziyad Al-Aly, a senior clinical epidemiologist at Washington University in St. Louis, who was not involved in the study.

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long COVID

Video | Long COVID is underdiagnosed, researchers say, and there’s work to be done to change that

Published October 29, 2025

Published by: CBC News
Published on: October 29, 2025

St. John’s hosted the 2025 Canadian Symposium on Long COVID earlier this month, a gathering of top researchers, clinicians, and people living with long COVID. As the CBC’s Adam Walsh reports, those on the symposium floor say more needs to be done to bring awareness to the condition as it continues to impact people of all ages.

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vaccines

Analysis: Last year’s COVID vaccines protected well against severe illness

Published October 28, 2025

Published by: CIDRAP
Published on: October 28, 2025
By Stephanie Soucheray

The updated 2024-25 COVID-19 vaccines provided 57% protection against hospitalization and death, although their effectiveness waned over time, according to a study yesterday in JAMA Internal Medicine.

The study assessed effectiveness against infection, emergency department (ED) visits, and hospitalization. Protection against infection and ED visits was 45%.

The study was based on outcomes seen among Nebraskan residents during the 2024-25 respiratory virus season and used hospital discharge data from member hospitals of the Nebraska Hospital Association and data from death certificates from the Nebraska Office of Vital Records.

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long COVID

Video | The Signal | Live [from] the 3rd Canadian Symposium on Long COVID

Published October 21, 2025

Published by: CBC News - NL - Newfoundland and Labrador
Published on: October 21, 2025

Today we bring you a live on location show at the 3rd Canadian Symposium on Long COVID. We talk to doctors, researchers, students and patients…

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research

A surprise bonus from COVID-19 vaccines: bolstering cancer treatment

Published October 20, 2025

Published by: Science
Published on: October 20, 2025
By Phie Jacobs

The innovative messenger RNA (mRNA) vaccines that thwarted the ravages of COVID-19 may also help fight tumors in cancer patients, according to a new analysis of medical records and studies in mice.

People with cancer who coincidentally received the mRNA shots before starting drugs designed to unleash the immune system against tumors lived significantly longer than those who didn’t get vaccinated, a research team announced yesterday at the European Society for Medical Oncology Congress in Berlin. Laboratory experiments by the group suggest the vaccines rev up the immune system, making even stubborn tumors more susceptible to treatment.

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indoor air quality

Federal Contract for up to $40 Million Fuels Research to Revolutionize Clean Indoor Air and Defend Against Next Pandemic

Published October 16, 2025

Published by: UC Davis
Published on: October 16, 2025
By Melody Warnick

When a public building catches fire, its built-in systems automatically respond: Smoke alarms blare, sprinklers kick on, and occupants quickly evacuate.

But what if the life-threatening danger isn’t fire but invisible airborne contaminants that can make occupants sick? Could a similar smart-building system monitor and improve the quality of the air indoors, where Americans spend 90 percent of their time?

With a contract for up to $40 million from the Advanced Research Projects Agency for Health (ARPA-H), an ambitious multi-institutional research team led by Virginia Tech and including researchers at the University of California, Davis, aims to create just such a system.

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war on science

Chaos following mass firings, rehirings at CDC

Published October 13, 2025

Published by: CIDRAP
Published on: October 13, 2025
By Stephanie Soucheray

Late Friday night more than 1,000 employees of the Centers for Disease Control and Prevention (CDC) were sent an email saying they had been let go due to reduction-in-force (RIF) efforts at the end of the second week of the federal government shutdown.

Some, however, were mistakenly fired and were rehired the next day, according to sources close to the situation.

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war on science

They Fought Outbreaks Worldwide. Now They’re Fighting for New Lives.

Published October 13, 2025

Published by: The New York Times
Published on: October 13, 2025
By Apoorva Mandavilli

The Trump administration’s new global health strategy, released last month, lists its most important goal as outbreak prevention and response, both to protect Americans and to safeguard the economy.

Containing the Ebola outbreak in West Africa a decade ago cost the United States $5.4 billion globally and more than $70 million domestically, the strategy report notes, adding, “As we have unfortunately seen all too frequently, an outbreak anywhere in the world can quickly become a threat to Americans.”

Yet, the freeze on America’s foreign aid in January disrupted many programs that extinguished outbreaks. Citing “waste, fraud and abuse” at federal agencies, the administration also laid off thousands of scientists, including many who worked on preventing and containing infectious diseases.

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research

Covid virus changes sperm in mice, may raise anxiety in offspring: study

Published October 11, 2025

Published by: France 24 / AFP
Published on: October 11, 2025

Sydney (AFP) – Covid-19 infection causes changes to sperm in mice that may increase anxiety in their offspring, a study released Saturday said, suggesting the pandemic’s possibly long-lasting effects on future generations.

Researchers at the Florey Institute of Neuroscience and Mental Health in Melbourne, Australia, infected male mice with the virus that causes Covid, mated them with females, and assessed the impacts on the health of their offspring.

“We found that the resulting offspring showed more anxious behaviours compared to offspring from uninfected fathers,” the study’s first author Elizabeth Kleeman said.

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long COVID

Scientists may have discovered what’s behind long COVID-related brain fog

Published October 9, 2025

Published by: Toronto Star
Published on: October 9, 2025
By Kevin Jiang

If you’re among the estimated one-in-five Canadians who developed long COVID symptoms after infection with COVID-19, you might be familiar with the memory problems, focusing difficulties and a whole slew of other cognitive impairments that have become emblematic of the condition — collectively known as “brain fog.”

But despite these cognitive symptoms being present in nearly 90 per cent of long COVID cases, the biological mechanism behind why brain fog happens — and how we can treat it — has remained largely elusive. Until now.

A new paper, published in peer-reviewed journal Brain Communications, found that people living with long COVID had more significantly higher levels of a certain brain receptor than their healthy peers. The more they had, the worse their symptoms tended to get, the study suggested.

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research

COVID ages women’s blood vessels, according to a study

Published October 2, 2025

Published by: Radio-Canada
Published on: October 2, 2025
By Marie-Pier Mercier

COVID-19 causes women’s blood vessels to age prematurely, according to an international study involving two researchers from Université Laval. The disease should therefore be considered an additional risk factor in cardiovascular health analyses. Specifically, in those who have developed severe symptoms, they warn.

The aging of blood vessels results in greater rigidity, which can increase the risk of certain cardiovascular diseases.

“The heart must work a little harder to propel blood through the arterial system, and this causes variations in pressure that can damage sensitive organs, including the brain and kidneys,” explains Catherine Fortier, a kinesiologist and researcher in vascular aging at the CHU de Québec-Université Laval.

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long COVID

Uncovering the Molecular Basis of Long COVID Brain Fog

Published October 1, 2025

Published by: Yokohama City University
Published on: October 1, 2025

Researchers use a specialized brain imaging technique to identify a potential biomarker and therapeutic target of Long COVID

Long COVID is a chronic condition that causes cognitive problems known as “brain fog,” but its biological mechanisms remain largely unclear. Now, researchers from Japan used a novel imaging technique to visualize AMPA receptors—key molecules for memory and learning—in the living brain. They discovered that higher AMPA receptor density in patients with Long COVID was closely tied to the severity of their symptoms, highlighting these molecules as potential diagnostic biomarkers and therapeutic targets.

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long COVID

Long Covid Risk for Children Doubles After a Second Infection, Study Finds

Published September 30, 2025

Published by: The New York Times
Published on: September 30, 2025
By Pam Belluck

Children and teenagers are twice as likely to develop long Covid after a second coronavirus infection as after an initial infection, a large new study has found.

The study, of nearly a half-million people under 21, published Tuesday in Lancet Infectious Diseases, provides evidence that Covid reinfections can increase the risk of long-term health consequences and contradicts the idea that being infected a second time might lead to a milder outcome, medical experts said.

Dr. Laura Malone, director of the Pediatric Post-Covid-19 Rehabilitation Clinic at Kennedy Krieger Institute in Baltimore, who was not involved in the study, said the findings echo the experience of patients in her clinic.

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vaccines

COVID vaccines may have averted thousands of hospital stays in infants, pregnant women over 18 months

Published September 30, 2025

Published by: CIDRAP
Published on: September 30, 2025
By Mary Van Beusekom

A US modeling study published yesterday in JAMA Pediatrics estimates that vaccinating pregnant women against COVID-19 prevented 7,000 hospitalizations in infants and 3,000 in pregnant women from January 2024 to May 2025.

The Stanford University–led research team analyzed COVID-NET surveillance data on COVID-19 hospitalization rates in infants younger than 6 months and incidence data on pregnant women aged 18 to 49 years under a relative risk of 2.65. The aim was to estimate the health impact of vaccination during pregnancy, mainly during the second or third trimester.

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research

Kids with COVID had a 50% to 60% higher risk of depression, anxiety in 2021, researchers say

Published September 10, 2025

Published by: CIDRAP
Published on: September 10, 2025
By Mary Van Beusekom

Relative to uninfected children, COVID-19 patients aged 8 to 17 years were at a 49% higher risk for new-onset depression or anxiety in 2021, rising to 59% in those with severe illness, according to a University of Utah study published this week in PLOS One.

The researchers mined the Utah All Payers Claims Database to explore the link between COVID-19 infection, illness severity, and risk of depression and anxiety among 154,565 school-aged youth who had private insurance or Medicaid coverage. The average participant age was 10.8 years in 2019, when the study period began, and 48% were girls.

Key contributors to mental illness among children include the pandemic’s direct impacts on daily life, such as school closures, isolation from peers, and disrupted family routines, the authors noted.

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Researchers use a specialized brain imaging technique to identify a potential biomarker and therapeutic target of Long COVID

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