Comments closedNext time you think of dismissing COVID as just another annoying common cold it may pay to visualise what you see so starkly in this paper, the virus moving freely around your body and finding a long-term home in all sorts of places where it can really cause trouble, including the brain and the heart.
This work further emphasises the need for individuals, and societies as a whole to take this infection more seriously and try and reduce the amount of transmission using the tools we currently have, most especially vaccination, clean indoor air approaches and well-fitted masks in crowded and poorly ventilated indoor settings.
Tag: research
If the world finds itself amid a flu pandemic in a few months, it won’t be a big surprise. Birds have been spreading a new clade of the H5N1 avian influenza virus, 2.3.4.4b, around the world since 2021. That virus spilled over to cattle in Texas about a year ago and spread to hundreds of farms across the United States since. There have been dozens of human infections in North America. And in some of those cases the virus has shown exactly the kinds of mutations known to make it better suited to infect human cells and replicate in them.
No clear human-to-human transmission of H5N1 has been documented yet, but “this feels the closest to an H5 pandemic that I’ve seen,” says Louise Moncla, a virologist at the University of Pennsylvania. “If H5 is ever going to be a pandemic, it’s going to be now,” adds Seema Lakdawala, a flu researcher at Emory University.
Comments closedSingle bird flu mutation could let it latch easily to human cells, study finds
Scientists from the Scripps Research Institute are reporting that it would take just a single mutation in the version of bird flu that has swept through U.S. dairy herds to produce a virus adept at latching on to human cells, a much simpler step than previously imagined.
To date, there have been no documented cases of one human passing avian influenza to another, the Scripps scientists wrote in their paper, which was published Thursday in the journal Science. The mutation they identified would allow the virus to attach to our cells by hitching itself to a protein on their surface, known as the receptor.
Comments closedAlmost a third of preteens, teens with long COVID still not recovered at 2 years, study shows
A new study from UK investigators shows that — while most COVID-19 patients ages 11 to 17 who reported long-COVID symptoms 3 months after the initial infection no longer experienced lingering symptoms at 2 years — 29% still did.
The findings, published in the journal Communications Medicine, come from the National Long COVID in Children and Young People cohort study, which followed up on thousands of young people after their COVID-19 diagnoses.
Comments closedExperimental study shows connection between COVID infection and age-related blindness
An experimental study in mice shows that SARS-CoV-2 infection can damage the retinas, with long-term implications for vision. Post-acute sequelae of SARS-CoV-2 infection include various neurocognitive symptoms, suggesting the virus can affect the central nervous system. The eyes are also part of the central nervous system, but little is known about the virus’s effects on these organs.
Comments closedSevere COVID-19 may be a risk factor for multiple sclerosis
COVID-19 may be a risk factor for multiple sclerosis (MS). This has been shown by new research at Örebro University and Örebro University Hospital, Sweden. The study is published in the journal Brain Communications.
“We saw a raised risk of MS among people who had severe COVID-19. However, only an extremely small number of people who had severe COVID-19 received a subsequent MS diagnosis,” says Scott Montgomery, professor in clinical epidemiology.
Comments closedLong a ‘Crown Jewel’ of Government, N.I.H. Is Now a Target
The National Institutes of Health, the world’s leading public funder of biomedical research, has an enviable track record. Research supported by the agency has led to more than 100 Nobel Prizes and has supported more than 99 percent of the drugs approved by federal regulators from 2010 to 2019.
No surprise, then, that the agency has been called “the crown jewel of the federal government.” But come January, when President-elect Donald J. Trump and congressional Republicans take charge, the N.I.H. may face a reckoning.
Comments closedStanford Doctor Tapped for Key Post by Trump Advocated for Letting COVID Spread
President-elect Donald Trump’s choice this week to lead the National Institutes of Health is a controversial Stanford researcher who was highly critical of the COVID-19 pandemic response, drawing pushback from the medical community and some still suffering from the long-term effects of the disease.
Dr. Jay Bhattacharya, a professor of health policy and senior fellow at the Stanford Institute for Economic Policy Research, was one of three co-authors of a 2020 letter that challenged policies like lockdowns and mask mandates, and called for speeding up herd immunity.
Comments closedAnalysis of 25 studies shows reduced risk of long COVID after vaccination
A new meta-analysis of studies involving more than 14 million people published in the Journal of Infection shows that COVID-19 vaccination is associated with a lower risk of developing long COVID, with two doses reducing the odds by 24% and one dose reducing the odds by 15%.
In the 25 studies published up to February 2024 that were included for analysis, long COVID was defined as persistent symptoms at 3 months or beyond, and all studies compared long-COVID symptoms between vaccinated and unvaccinated groups, with the number of doses received by participants specified. All studies included were observational trials and included in total 14,128,260 participants.
Comments closedCovid Can Raise the Risk of Heart Problems for Years
Since nearly the start of the pandemic, scientists have known that a Covid-19 infection increases the risk of heart problems. A growing body of research now suggests that this risk can last until well after the infection has cleared.
One recent study, conducted by researchers at the University of Southern California and Cleveland Clinic, found that a Covid-19 infection doubled the risk of a major cardiovascular event for up to three years afterward. What’s more, the study found that infections severe enough to require hospitalization increased the likelihood of cardiac events as much as — or more than — having previously had a heart attack did.
Comments closedBird flu in Canada may have mutated to become more transmissible to humans
The teenager hospitalized with bird flu in British Columbia, Canada, may have a variation of the virus that has a mutation making it more transmissible among people, early data shows – a warning of what the virus can do that is especially worrisome in countries such as the US where some H5N1 cases are not being detected.
The US “absolutely” is not testing and monitoring bird flu cases enough, which means scientists could miss mutated cases like these, said Richard Webby, a virologist at St Jude children’s research hospital’s department of infectious diseases.
Comments closedLong Covid could cost the economy billions every year
Working days lost to long Covid could be costing the economy billions of pounds every year as patients struggle to cope with symptoms and return to work, finds a new study led by UCL researchers.
Comments closedWastewater testing for avian influenza to begin in some Ontario communities
As bird flu infections continue to rise among livestock and humans in the United States, surveillance is ramping up in Canada.
Wastewater testing for the H5N1 bird flu virus is set to begin in the coming weeks in Ontario communities considered at high risk, said Rob Delatolla, whose University of Ottawa lab will lead the wastewater surveillance as part of a research program based at the University of Guelph. That will likely mean testing wastewater in communities in agricultural regions of the province. It is unclear whether there will also be testing in larger cities.
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