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Tag: research

Report: More than 200 symptoms tied to long COVID

Today a new report from the National Academies of Sciences, Engineering, and Medicine presents a number of conclusions about long-COVID diagnosis, symptoms, and impact on daily function, including that the condition can cause more than 200 symptoms, and that a positive COVID-19 test is not necessary to make a long-COVID diagnosis.

The findings are meant to guide the Social Security Administration (SSA) and are published one week before the National Academies of Sciences, Engineering, and Medicine is set to offer a new single definition of long COVID that can be used across US governmental groups as a way to streamline treating the condition in the years to come.

“This report offers a comprehensive review of the evidence base for how Long COVID may impact a patient’s ability to engage in normal activities, such as going to work, attending school, or taking care of their families,” said Victor J. Dzau, MD, president of the National Academy of Medicine, in a National Academies press release. “Its findings will be useful to anyone attempting to understand how Long COVID may affect the millions of people in the U.S. who have reported symptoms.”

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‘I was shocked’: Ontario to cancel widely used wastewater surveillance program

The Ontario government is shutting down the wastewater surveillance program that has provided early warning for incoming waves of COVID-19 and a growing list of other infectious diseases since it was developed.

By the time it ends on July 31, the program that got its start in Ottawa early in the pandemic will be one of the biggest in the world to monitor the spread of infectious diseases through wastewater. Researchers were told of the decision to end funding last week.

Its closure comes at a time when COVID-19 is again beginning to spread through the world after a lull and when the United States and other countries are ramping up wastewater surveillance programs to warn about the possible spread of H5N1 avian influenza.

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COVID can cause new health problems to appear years after infection, according to a study of more than 130,000 patients

Even as national institutions struggle to coordinate meaningful trials for possible long COVID treatments, researchers continue to tally the damage. New findings suggest that the disease’s reach isn’t merely long—it’s still growing.

Three years after their initial bouts with COVID-19, patients who’d once been hospitalized with the virus remained at “significantly elevated” risk of death or worsening health from long COVID complications, according to a paper published May 30 in Nature Medicine.

Even among those whose initial cases didn’t require a hospital stay, the threat of long COVID and several of its associated issues remained real, the researchers found. And cumulatively, at three years, long COVID results in 91 disability-adjusted life years (DALY) per 1,000 people—DALYs being a measure of years lost to poor health or premature death. That is a higher incidence than either heart disease or cancer.

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Masks work, our comprehensive review has found

When a Texan farm worker caught bird flu from cattle recently, social media was abuzz with rumours. While bird flu is not a human pandemic, scientists and policymakers the world over are keen to prepare as best they can for when such a pandemic emerges – a tricky task, given that science is messy, policy must be pragmatic and people’s values don’t always align.

It’s time for masks to enter the chat. At the beginning of a pandemic caused by a novel or newly mutated virus, there may be no vaccine, no firm knowledge about how bad things will get and no specific treatment. Slowing transmission until more is known will be critical.

Getting most people to wear a mask could nip the outbreak in the bud, preventing a pandemic or lessening its impact. Wearing a mask is inconvenient, but not as inconvenient as lockdowns.

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Four Years On, Covid-19 Remains a Worse Killer Than the Flu, US Study Finds

We did the 2024 Covid-versus-flu rematch thinking that we may find that risk of death in Covid may have sufficiently declined to become equal with the risk of death from flu. But the reality remains that Covid carries a higher risk of death than the flu. […]

Overall, I think this means that we still need to take Covid seriously. Trivializing it as an inconsequential ‘cold,’ as we often hear, doesn’t mesh or align with reality.

— Dr. Ziyad Al-Aly
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COVID virus can infect your eyes and damage vision

The virus that causes COVID-19 can breach the protective blood-retinal barrier, leading to potential long-term consequences in the eye, new research shows.

The blood-retinal barrier is designed to protect our vision from infections by preventing microbial pathogens from reaching the retina where they could trigger an inflammatory response with potential vision loss.

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Data: Heart-failure patients have 82% better odds of living longer if vaccinated against COVID

The first study of COVID-19 vaccine effectiveness in a large population of adult heart-failure patients suggests that vaccinated participants are 82% more likely to live longer than their unvaccinated peers, according to an analysis presented over the weekend at the Heart Failure 2024 scientific congress of the European Society of Cardiology (ESC) in Lisbon, Portugal.

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CDC launching wastewater dashboard to track bird flu virus spread

Reluctance among dairy farmers to report H5N1 bird flu outbreaks within their herds or allow testing of their workers has made it difficult to keep up with the virus’s rapid spread, prompting federal public health officials to look to wastewater to help fill in the gaps.

On Tuesday, the Centers for Disease Control and Prevention is expected to unveil a public dashboard tracking influenza A viruses in sewage that the agency has been collecting from 600 wastewater treatment sites around the country since last fall.

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Researchers estimate vaccines have saved 154 million lives over past half-century

An international team of health and medical researchers including workers at the WHO, working with economists and modeling specialists, has found that the use of vaccines to prevent or treat disease has saved the lives of approximately 154 million people over the past half-century.

In their study, published in The Lancet, the group used mathematical and statistical modeling to develop estimates for lives saved due to vaccines and then added them together to find the total.

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What are the most reliable rapid antigen tests?

A new study has analysed 26 RATs from Australia and Canada, finding only six could effectively detect the lowest concentrations of COVID-19.

Patients across the globe have come to rely on rapid antigen tests (RATs) to confirm a COVID-19 diagnosis, but a new Australian study has revealed most are not producing accurate results.

Researchers from James Cook University (JCU) say they were left ‘shocked’ after an analysis of 26 RATs from Australia and Canada found just six were effective at detecting the lowest concentration of COVID-19.

One Canadian test failed to detect the COVID-19 protein entirely at any level of concentration.

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Scientists, clinicians across Canada preparing for future pandemic threats

Nearly $574 million will be doled out to researchers across the country for projects aimed at ramping up Canada’s preparedness for future health emergencies, including the next pandemic, the federal government announced on Monday.

One of the 19 projects is a national network of existing emergency departments and primary-care clinics, called Prepared, that will screen for any new viruses or pathogens that start to appear in patients.

“As a public health specialist and as a practising physician, I would very much anticipate there being another respiratory pandemic in the future. The challenge is we don’t know when it will be or what it will be,” said Dr. Andrew Pinto, Prepared project lead and a family physician at St. Michael’s Hospital in Toronto.

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Common diabetes drug lowers SARS-CoV-2 levels, clinical trial finds

Today, researchers from the University of Minnesota published evidence that the common diabetes drug metformin decreases the amount of SARS-CoV-2 in the body and helps reduce the risk of rebound symptoms if given early in the course of non-severe illness.

The study, published in Clinical Infectious Diseases, suggests metformin may also help prevent long COVID.

The researchers tested metformin against a placebo in 999 adults infected with COVID-19. More than 50% of the study enrollees were vaccinated, and treatment took place when the Omicron variant was the most dominant strain in the United States.

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International study highlights best RATs

A ground-breaking study by James Cook University researchers has produced damning findings on several COVID-19 Rapid Antigen Tests (RATs) available in Australia and overseas.

The new joint study by JCU and National Research Council Canada analysed 16 RATs approved by Australia’s Therapeutic Goods Administration (TGA) and 10 by Health Canada, using a JCU-developed COVID-19 protein and its Canadian counterpart as reference materials.

Out of the total 26 RATs compared, only six were found to be effective at detecting the lowest concentration of the COVID-19 reference proteins in the dilution series used for benchmarking.

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What we’re starting to learn about H5N1 in cows, and the risk to people

The H5N1 bird flu virus has been around for decades, and the damage it wreaks on chickens and other poultry is well documented. But the recent discovery that the virus has jumped into dairy cattle — whose udders seem to be where the virus either infects or migrates to — has dumbfounded scientists and agricultural authorities.

Questions for which there are pretty clear answers when it comes to birds are suddenly unsettled science in cows. How are they getting infected? Are they transmitting the virus cow to cow, or are human actions — activities that are part of the day-to-day of farming — serving as an unrecognized amplifier of viral transmission? In the interface between infected cows and humans, how might people be at risk? Does consuming milk laced with live H5 virus pose a hazard?

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Scientists discover higher levels of CO2 increase survival of viruses in the air and transmission risk

A new study has revealed for the first time the vital role carbon dioxide (CO2) plays in determining the lifespan of airborne viruses – namely SARS-CoV-2, the virus that causes COVID-19.

It clearly showed keeping CO2 levels in check helps to reduce virus survival, and therefore the risk of infection.

The research, led by the University of Bristol and published today in Nature Communications, shows how CO2 is a major factor in prolonging the life of SARS-CoV-2 variants present in tiny droplets circulating in the atmosphere.

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Video | Akiko Iwasaki on what causes long COVID, brain fog, the Yale Paxlovid study and long COVID treatments

What causes long COVID? Is long COVID dangerous? Who is most likely to get long COVID? Any pediatric long COVID news? What can be done for long term COVID?

Our guest is Akiko Iwasaki, PhD, Sterling Professor of Immunobiology at Yale University. AMA Chief Experience Officer Todd Unger hosts.

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