Three new studies shed new light on long COVID in the United States, with one finding that two thirds of severely ill patients reported persistent impairments for up to 1 year, another showing that US veterans were at three times the risk of preventable hospitalization in the month after infection, and the last revealing that one third of COVID-19 survivors had lingering symptoms at one time.
Comments closedCOVID-19 became the second leading cause of death globally in the year after it was declared a pandemic, according to a study published in the Lancet.
While heart disease remained the top killer, COVID “radically altered” the main five causes of death for the first time in 30 years, displacing stroke, the publication said. In 2021, 94 in every 100,000 people died from COVID, on an age-standardized basis.
Comments closedComments closedIt’s an invisible and new condition. Many people don’t believe that long COVID is real or exists. And unfortunately, that permeates through the healthcare system. Even outside of the medical system, there is a broader societal awareness that is lacking.
A new study, looking at the replication stage of the SARS-CoV-2 virus that causes COVID-19, discovered important mechanisms in its replication that could be the foundation for new antiviral therapies.
The study, which set out to investigate how the SARS-CoV-2 virus replicates once it enters the cells, has made surprising discoveries that could be the foundation for future antiviral therapies. It also has important theoretical implications as the replication of the SARS-CoV-2 virus has, so far, received less attention from researchers.
Comments closedA recent USC study provides new information about why SARS-CoV-2, the virus behind the COVID-19 pandemic, may elicit mild symptoms at first but then, for a subset of patients, turn potentially fatal a week or so after infection. The researchers showed that distinct stages of illness correspond with the coronavirus acting differently in two different populations of cells.
The study, published in Nature Cell Biology, may provide a roadmap for addressing cytokine storms and other excessive immune reactions that drive serious COVID-19.
The team found that when SARS-CoV-2 infects its first-phase targets, cells in the lining of the lung, two viral proteins circulate within those cells—one that works to activate the immune system and a second that, paradoxically, blocks that signal, resulting in little or no inflammation.
Comments closedA study of more than 11,000 Australians who tested positive to COVID-19 in 2022 has revealed almost one-in-five were still experiencing ongoing symptoms three months after their initial diagnosis, according to new research from The Australian National University (ANU).
The study was conducted in Western Australia (WA), with participants drawn from the almost 71,000 adults who tested positive to COVID-19 in WA between 16 July 2022 and 3 August 2022.
Lead researcher, Dr Mulu Woldegiorgis, said the results show the risk of developing long COVID from the Omicron variant is higher than previously thought.
Comments closedThe Omicron coronavirus variant could be causing more cases of long COVID than earlier versions of the disease, scientists say.
A study of more than 11,000 Western Australians infected in 2022 found almost one in five continued to suffer symptoms three months after they initially tested positive.
Epidemiologist Mulu Woldegiorgis said the findings show the Omicron variant puts patients at greater risk of developing long COVID than previously thought.
“It is more than double the prevalence reported in a review of Australian data from earlier in the pandemic, and higher than similar studies done in the UK and Canada,” she said on Thursday.
Comments closedA study today in Clinical Infectious Diseases conducted across 12 tertiary care pediatric hospitals in Canada and the United States shows that asymptomatic children with COVID-19, especially preschoolers, contribute significantly to household transmission.
The researchers discovered that 10.6% of exposed household contacts developed symptomatic illness within 14 days of exposure to asymptomatic test-positive children, a rate higher than expected.
“We determined that the risk of developing symptomatic illness within 14 days was 5 times greater among household contacts of asymptomatic SARS-CoV-2–positive children,” the authors wrote.
They also found that 6 of 77 asymptomatic SARS-CoV-2–infected children during a 3-month follow-up developed long COVID, or 7.8% of them.
Comments closedComments closedSome people who had Long Covid early in 2020 are still not well. So the experience of being not listened to and not believed has been very harmful for them alongside the very considerable health impacts that they’ve had from Long Covid. […] The cost of inaction is going to be very high and that’s going to be a human cost and a financial cost.
COVID-19 is a respiratory disease. Yet, from the earliest days of the pandemic, the cardiovascular risks associated with SARS-CoV-2 infection were clear: individuals with severe cases of COVID-19 often died from cardiovascular complications, and those with pre-existing cardiovascular disease were more likely to have severe illness or die.
In short, the cardiovascular system has played a central role in COVID-19 since the beginning.
It is not surprising that as debate over COVID-19 and vaccines flared that cardiovascular disease was a central issue. Those opposed to vaccination often make claims of cardiovascular risks that exceed any benefits. But when data on COVID-19, vaccines and cardiovascular health are reviewed, the conclusions are clear: vaccines are safe and effective at reducing the cardiovascular complications that are a hallmark of COVID-19.
Comments closedTaken together, these studies show that COVID-19 poses a serious risk to brain health, even in mild cases, and the effects are now being revealed at the population level. […]
The growing body of research now confirms that COVID-19 should be considered a virus with a significant impact on the brain. The implications are far-reaching, from individuals experiencing cognitive struggles to the potential impact on populations and the economy.
The proportion of children infected with COVID-19 while riding a bus to a school in Germany was about four times higher than in peers who didn’t ride the bus, illustrating efficient transmission during multiple short rides on public transport, finds a study published this week in Emerging Infectious Diseases.
A team led by researchers from the Robert Koch Institute in Berlin and public health officials used surveillance data, lab analyses, case-patient and household interviews, a cohort study of all students in grades 1 to 4, and a cohort study of bus riders to investigate a 2021 COVID-19 outbreak that involved an infected bus driver and his passengers. The rides lasted 9 to 18 minutes, and multiple schools in a single district were involved.
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