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Tag: SARS-CoV-2

Increased levels of Alzheimer’s-linked protein found in some with long COVID

A study of 227 individuals who experienced neurocognitive difficulties post COVID-19 infection—such as headaches, vertigo, balance dysregulation, changes in taste/smell, and brain fog—displayed a significant increase in their blood plasma of a crucial protein called tau, which is found in nerves and especially in the brain. Excess levels of tau are linked to neurodegenerative diseases and found in many Alzheimer’s patients.

Published in eBioMedicine, the study suggests that people who experience long COVID neurocognitive symptoms could be at further risk for neurodegenerative diseases.

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Moderna COVID vaccine 53% effective against adult hospitalization in 2024-25 season, data suggest

A large observational study using US healthcare claims and electronic health record data suggests that Moderna’s updated 2024-25 COVID vaccine was 39% effective at preventing medically attended illness among adults and 53% effective against hospitalization, particularly those at high risk for severe disease.

The study, led by scientists from the vaccine manufacturer and published late last week in Infectious Diseases and Therapy, analyzed outcomes among 596,248 adults who received the updated mRNA-1273 vaccine, which targeted the Omicron KP.2 variant, from August 2024 to April 2025. Vaccinated people were matched 1:1 with unvaccinated counterparts.

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Yellowknife adds more flu and Covid shot walk-in clinics

Yellowknife public health workers say two walk-in clinics for flu and Covid-19 shots will take place this week.

The first runs from 9am-4pm on Monday including the lunch hour, staff said in a Monday morning email, and the second operates to the same times on Friday, January 16.

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‘Incomprehensibly stupid:’ How U.S. cuts in vaccine recommendations will impact Canadians

Canadian doctors are warning that a new U.S. policy which slashes the number of vaccines universally recommended to all children could have devastating, and potentially deadly effects in Canada, including increasing disease spread through American travellers visiting north of the border.

“This was just incomprehensibly stupid. I was horrified,” said family doctor and former president of the Ontario Medical Association, Dr. Sohail Gandhi in an interview with CTV News Saturday. “Children in the U.S. are going to die as a result of this move – and, worse, some children are going to have lifelong complications as a result of this move.”

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German health minister rejects US counterpart’s COVID claims

US Health Secretary Robert F Kennedy Jr has claimed that doctors in Germany who issued COVID-19 vaccine exemptions are facing legal action. Health Minister Nina Warken has hit back vehemently at the accusations.

German Health Minister Nina Warken has rejected accusations by US Health Secretary Robert F Kennedy Jr that doctors in Germany have faced legal action for issuing vaccine and mask exemptions during the coronavirus pandemic.

Kennedy, a known vaccine skeptic, posted a video on X on Saturday in which he says: “I’ve learned that more than a thousand German physicians, and thousands of their patients, now face prosecution and punishment for issuing exemptions from wearing masks or getting COVID-19 vaccines during the pandemic.”

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Face masks ‘inadequate’ and should be swapped for respirators, WHO is advised

Experts are urging guideline changes on what health professionals should wear to protect against flu-like illnesses including Covid

Surgical face masks provide inadequate protection against flu-like illnesses including Covid, and should be replaced by respirator-level masks – worn every time doctors and nurses are face to face with a patient, according to a group of experts urging changes to World Health Organization guidelines.

There is “no rational justification remaining for prioritising or using” the surgical masks that are ubiquitous in hospitals and clinics globally, given their “inadequate protection against airborne pathogens”, they said in a letter to WHO chief Dr Tedros Adhanom Ghebreyesus.

“There is even less justification for allowing healthcare workers to wear no face covering at all,” they said.

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In utero COVID exposure linked to brain changes, developmental delays, anxiety, and depression

In utero SARS-CoV-2 exposure may predispose children to altered brain volumes, impaired cognition, and internalizing emotional problems such as anxiety and depression, researchers from Children’s National Hospital and George Washington University write in Brain, Behavior, and Immunity.

The team enrolled 39 mother-baby pairs in Washington, DC, who had been exposed to COVID-19 during pregnancy from 2020 to 2022 and compared them with 103 normative pairs from before the pandemic (2016 to 2019). None of the infected women had been vaccinated against SARS-CoV-2.

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COVID-19 Is Six Today. What We’ve Learned

We need cleaner air, which requires changes in medical culture.

Last year on this date, I published a Tyee article about the fifth anniversary of the first public announcement of what we now know as COVID-19.

My conclusions then were that we hadn’t learned much from the experience. A year later, many of us have unlearned the value of vaccination. Outbreaks of measles and whooping cough have predictably followed. Alberta has stopped reporting COVID-19 in hospitals.

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As H3N2 sweeps across Canada, what to know about flu’s heart attack risk

It’s more than just a bad cold: influenza can also raise your risk of a heart attack shortly after an infection, medical experts are warning as the H3N2 strain spreads rapidly in Canada.

At the same time, flu season is coinciding with another risk factor for heart attacks – shovelling snow.

“Any time you get an infection, including a viral infection, there’s the release in your body of molecules that both trigger inflammation and sustain inflammation. And part of that is an increased tendency for your blood to clot,” said Dr. Fahad Razak, internal medicine physician at St. Michael’s Hospital and professor at the University of Toronto.

“That can have immediate effects within the weeks following an infection, resulting in things like strokes or heart attacks.”

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Schools must improve air quality to slow spread of respiratory illness, advocates say

Heather Hanwell’s 12-year-old daughter recently missed almost two weeks of school after being hit hard by a viral infection. She’s among many parents who are caring for sick kids this flu season, which so far has seen a surge of cases among school-age children.

But the experience was particularly frustrating for Dr. Hanwell, an epidemiologist who says that improving the air quality in schools would help reduce the spread of contagious respiratory illnesses.

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Schools have become cesspools for cold and flu, but they don’t have to be: Ontario School Safety

The volunteer-led organization Ontario School Safety is renewing calls to the Ontario government to improve indoor air quality in schools.

The call comes as Ontario sees a rapid increase in cases of the flu, particularly impacting young children.

In April, 2021, the Government of Ontario announced it was investing over $130 million, in addition to funds from the Canadian government, to upgrade school infrastructure to protect children from COVID-19. The majority of this funding was earmarked for ventilation projects to improve indoor air quality.

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Workplace exposures tied to higher risk of long COVID

Work-related factors may increase the risk of developing long COVID, according to a new population-based study from Spain.

The findings, published in BMJ Occupational & Environmental Medicine, suggest that the primary work-related drivers of increased long COVID risk were irregular or limited use of respirators, close contact with coworkers and/or the public, inability to physical distance, and use of public transportation to commute to work.

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Masks now required at all Nova Scotia Health sites

Nova Scotia Health says masking is required throughout all its facilities beginning Thursday.

However, the health authority says masks are not required in:

  • administrative buildings
  • private offices, nursing stations, or conference rooms (if no patients are present)
  • cafeterias (when people are seated)
  • patient bed-spaces (for patients, partners, and visitors)
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Alberta quietly ends public reporting of COVID outbreaks in acute care

Alberta’s government said the province is under no legal obligation to continue publishing the data in a “post-pandemic context.”

Alberta’s government quietly eliminated its public reporting dashboard of COVID-19 outbreaks in acute care facilities, saying the province is under no legal obligation to continue publishing the data in a “post-pandemic context.”

Alberta Health Services’ (AHS) acute-care outbreaks webpage provided weekly public reports on COVID-19 outbreaks in AHS and Covenant Health facilities, including the location where an outbreak had been reported, the date the outbreak was declared, the number of units affected, and how many patients and health-care workers were infected.

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Most Canadians still confident in vaccines, but hesitancy has increased, poll says

TORONTO – A new poll says that about three-quarters of Canadian adults still have confidence in vaccines, but hesitancy has increased over the last five years.

The survey conducted by Leger Healthcare and released on Tuesday says 74 per cent of respondents said they were either “very confident” (42 per cent) or “somewhat confident” (32 per cent) in the safety and effectiveness of vaccines.

But about a quarter of respondents said they are less confident than they were before.

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Occupational Factors Strongly Influence Long-COVID Risk

A large Catalan cohort study shows that healthcare, social care, education, retail, and transport workers are at higher risk for Long-COVID

Work-related factors play a significant and independent role in the risk of developing Long-COVID, shows a new study based on the COVICAT cohort and led by the Barcelona Institute for Global Health (ISGlobal), a centre supported by “la Caixa” Foundation, in collaboration with the University of Turin and the Germans Trias i Pujol Institute (IGTP). The findings, published in BMJ Occupational & Environmental Medicine, highlight that a substantial share of Long-COVID could be prevented through targeted workplace measures and policies.

The public health impact of Long-COVID is far from over. Beyond ongoing infections that continue to cause illness and deaths worldwide, millions of people are living with lasting health consequences. Globally, around 6 in every 100 COVID-19 cases develop Long-COVID, amounting to 400 million affected people and an annual economic impact of roughly 1 trillion dollars, or 1% of the global economy.

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COVID-19 leaves a lasting mark on the human brain

COVID-19 does not just affect the respiratory system, but also significantly alters the brain in people who have fully recovered from the infectious disease, highlighting the long-term neurological impact of the virus.

Researchers from Griffith University’s National Centre for Neuroimmunology and Emerging Disease (NCNED) used advanced MRI techniques to ascertain the neurological implications of COVID-19 compared with those who had never been infected.

The research provided compelling evidence that even in the absence of ongoing symptoms, prior infection with the virus could leave a measurable imprint on the brain.

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COVID shot reduces risk of severe illness, premature birth in pregnancy, study says

TORONTO – A new study says the COVID-19 vaccine protects pregnant women from getting severely ill or giving birth prematurely.

Researchers with the Canadian Surveillance of COVID-19 in Pregnancy (CANCOVID-Preg) program, led by the University of British Columbia analyzed public health and clinical records of 19,899 pregnant people diagnosed with COVID between April 5, 2021 and Dec. 31, 2022.

That time period covered infections with both Delta and Omicron variants in eight provinces and one territory.

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