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Tag: United States

NIH cuts billions of dollars in biomedical funding, effective immediately

The Trump administration is cutting billions of dollars in biomedical research funding, alarming academic leaders who said it would imperil their universities and medical centers and drawing swift rebukes from Democrats who predicted dire consequences for scientific research.

The move, announced Friday night by the National Institutes of Health, drastically cuts NIH’s funding for “indirect” costs related to research. These are the administrative requirements, facilities and other operations that many scientists say are essential but that some Republicans have claimed are superfluous.

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I Ran U.S.A.I.D. Killing It Is a Win for Autocrats Everywhere.

We are witnessing one of the worst and most costly foreign policy blunders in U.S. history. Less than three weeks into Donald Trump’s second term, he, Elon Musk and Secretary of State Marco Rubio have halted the U.S. Agency for International Development’s aid programs around the world. In so doing, they have imperiled millions of lives, thousands of American jobs and billions of dollars of investment in American small businesses and farms while severely undermining our national security and global influence — all while authoritarians and extremists celebrate their luck.

I am shocked by the gleeful assault perpetrated by our own government against U.S.A.I.D.’s programs and the public servants who work on them. But after running the agency for four years, I am not surprised that the attacks are being cheered by Moscow and Beijing. They understand what those seeking to dismantle the agency are desperate to hide from the American people: U.S.A.I.D. has become America’s superpower in a world defined by threats that cross borders and amid growing strategic competition.

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Nasal COVID-19 vaccine based on WashU technology to enter U.S. clinical trials

A nasal vaccine for COVID-19 – based on technology developed at Washington University in St. Louis – is poised to enter a phase 1 clinical trial in the U.S. after an investigational new drug application from Ocugen, Inc. was approved by the Food and Drug Administration (FDA). Ocugen, a U.S.-based biotechnology company, licensed the innovative technology from WashU in 2022.

The trial will be sponsored and conducted by the National Institute of Allergy and Infectious Diseases (NIAID), of the National Institutes of Health (NIH). The FDA’s action is a critical first step toward initiation of the phase 1 trial, planned for this spring.

While cases of COVID-19 have fallen dramatically since the early years of the pandemic, the virus continues to circulate and still causes significant illnesses and deaths. The nasal vaccine technology is designed to induce strong immunity in the nose and upper respiratory tract, right where the virus enters the body, thereby potentially stopping transmission of the virus in addition to reducing serious illness and death. Most COVID-19 vaccines are injected into the arm or leg, and while they are effective at reducing illness and death, they do not halt transmission. The new trial will evaluate the safety and efficacy of the vaccine administered via two routes: inhaled into the lungs and sprayed into the nose.

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Deaths predicted amid the chaos of Elon Musk’s shutdown of USAid

The impact of the billionaire’s declaration has been swift and brutal, with food and crucial drugs abandoned in warehouses, vital programmes closed and workers laid off

Critical supplies of life-saving medicines have been blocked and children left without food and battling malnutrition as multiple effects were reported across the globe after Elon Musk resolved to shut down the US government’s pre-eminent international aid agency.

Chaotic scenes were seen in scores of countries as aid organisations warned of the risk of escalating disease and famine along with disastrous repercussions in areas such as family planning and girls’ education, after President Donald Trump’s decision to freeze funding to USAid. In 2023, the agency managed more than $40bn (£32bn).

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CDC Data Are Disappearing

Last night, scientists began to hear cryptic and foreboding warnings from colleagues: Go to the CDC website, and download your data now. They were all telling one another the same thing: Data on the website were about to disappear, or be altered, to comply with the Trump administration’s ongoing attempt to scrub federal agencies of any mention of gender, DEI, and accessibility. “I was up until 2 a.m.,” Angela Rasmussen, a virologist at the Vaccine and Infectious Disease Organization at the University of Saskatchewan who relies on the CDC’s data to track viral outbreaks, told me. She archived whatever she could.

What they feared quickly came to pass. Already, content from the CDC’s Youth Risk Behavior Surveillance System, which includes data from a national survey, has disappeared; so have parts of the Agency for Toxic Substances and Disease Registry’s Social Vulnerability Index and the Environmental Justice Index. The CDC’s landing page for HIV data has also vanished. And the agency’s AtlasPlus tool, which contains nearly 20 years of CDC surveillance data on HIV, hepatitis, sexually transmitted infections, and tuberculosis, is down. Several scientists I talked with told me they had heard directly from contacts at the CDC that the agency has directed employees to scrub any mention of “gender” from its site and the data that it shares there, replacing it with “sex.”

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RFK Jr. kept asking to see the science that vaccines were safe. After he saw it, he dismissed it

WASHINGTON (AP) — The man who hopes to be President Donald Trump’s health secretary repeatedly asked to see “data” or “science” showing vaccines are safe – but when an influential Republican senator showed him evidence, he dismissed it.

Robert F. Kennedy Jr. spent two days this week insisting to senators that he’s not anti-vaccine. He said that he instead supports vaccinations and will follow the science in overseeing the $1.7 trillion Department of Health and Human Services, which, among other duties, oversees vaccine research, approval and recommendations.

But Kennedy repeatedly refused to acknowledge scientific consensus that childhood vaccines don’t cause autism and that COVID-19 vaccines saved millions of lives, and he falsely asserted the government has no good vaccine safety monitoring. While appearing to ignore mainstream science, he cited flawed or tangential research to make his points, such as suggesting Black people may need different vaccines than whites.

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Kennedy faces tough questioning on vaccine views at HHS confirmation hearing

RFK Jr. has a well-documented history of spreading dangerous disinformation on vaccines and public health interventions, leaving vulnerable communities unprotected and placing millions of lives at risk. His appointment is a direct threat to the safety of our patients and the public at large.

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Video | Caroline Kennedy accuses cousin RFK Jr. of being a ‘predator’

CNN’s Arlette Saenz reports on video shared by Caroline Kennedy warning senators to reject her cousin Robert F. Kennedy Jr.’s nomination to be Health and Human Services secretary ahead of confirmation hearings on Wednesday.

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Trump Administration Halts H.I.V. Drug Distribution in Poor Countries

The Trump administration has instructed organizations in other countries to stop disbursing H.I.V. medications purchased with U.S. aid, even if the drugs have already been obtained and are sitting in local clinics.

The directive is part of a broader freeze on foreign aid initiated last week. It includes the President’s Emergency Plan for AIDS Relief, the global health program started by George W. Bush that is credited with saving more than 25 million lives worldwide.

The administration had already moved to stop PEPFAR funding from moving to clinics, hospitals and other organizations in low-income countries.

Appointments are being canceled, and patients are being turned away from clinics, according to people with knowledge of the situation who feared retribution if they spoke publicly. Many people with H.I.V. are facing abrupt interruptions to their treatment.

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National Science Foundation freezes grant review in response to Trump executive orders

The National Science Foundation canceled all of its grant review panels this week, as the organization works to align its grantmaking process with new executive orders from the Trump administration.

The NSF funds a wide range of scientific research through grants to universities and research institutions. It convenes panels of experts to weigh the merits of those proposals, ultimately informing which receive federal funding. It has a budget of around $9 billion.

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‘A Dangerous Virus’: Bird Flu Enters a New Phase

When bird flu first struck dairy cattle a year ago, it seemed possible that it might affect a few isolated herds and disappear as quickly as it had appeared.

Instead, the virus has infected more than 900 herds and dozens of people, killing one, and the outbreak shows no signs of abating.

A human pandemic is not inevitable, even now, more than a dozen experts said in interviews. But a series of developments over the past few weeks indicates that the possibility is no longer remote.

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Trump administration’s abrupt cancellation of scientific meetings prompts confusion, concern

A flurry of scientific gatherings and panels across federal science agencies were canceled on Wednesday, at a time of heightened sensitivity about how the Trump administration will shift the agencies’ policies and day-to-day affairs.

Several meetings of National Institutes of Health study sections, which review applications for fellowships and grants, were canceled without being rescheduled, according to agency notices reviewed by STAT. A Feb. 20-21 meeting of the National Vaccine Advisory Committee, a panel that advises the leadership of the Department of Health and Human Services on vaccine policy, was also canceled. So was a meeting of the Presidential Advisory Council for Combating Antibiotic-Resistant Bacteria that was scheduled for Jan. 28 and 29.

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WHO regrets Trump move to pull US from organization

Trump on Monday signed an executive order directing the United States to withdraw from the WHO, a body he has repeatedly criticized over its handling of the Covid-19 pandemic.

Speaking at the White House after his inauguration, Trump said the United States was paying far more to the United Nations body than China, adding: “World Health ripped us off.”

Washington, comfortably the biggest financial contributor to the Geneva-based organization, provides substantial support that is critical to the WHO’s operations.

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Trump officials pause health agencies’ communications, citing review

The Trump administration has instructed federal health agencies to pause all external communications, such as health advisories, weekly scientific reports, updates to websites and social media posts, according to nearly a dozen current and former officials and other people familiar with the matter.

The instructions were delivered Tuesday to staff at agencies inside the Department of Health and Human Services, including the Food and Drug Administration, the Centers for Disease Control and Prevention and the National Institutes of Health, one day after the new administration took office, according to the people with knowledge, who spoke on the condition of anonymity to describe private conversations. Some of them acknowledged that they expected some review during a presidential transition but said they were confused by the pause’s scope and indeterminate length.

The health agencies are charged with making decisions that touch the lives of every American and are the source of crucial information to health-care providers and organizations across the country.

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As Polio Survivors Watch Kennedy Confirmation, All Eyes Are on McConnell

Their numbers are dwindling now, the faded yellow newspaper clippings reporting their childhood trips to the hospital tucked away in family scrapbooks. Iron lungs, the coffin-like cabinet respirators that kept many of them alive, are a thing of the past, relegated to history books and museums. Some feel the world has forgotten them.

Now the nation’s polio survivors are reliving their painful memories as they watch events in Washington, where the Senate will soon consider the nomination of Robert F. Kennedy Jr., a fierce critic of vaccines, to be the nation’s next health secretary. And they are keeping a close eye on one of their own: Senator Mitch McConnell, the former Republican leader.

It has been nearly 70 years since Dr. Jonas Salk’s polio vaccine was pronounced “80 to 90 percent effective” against the paralytic form of the disease. Although the government does not keep official numbers, advocacy groups say there are an estimated 300,000 survivors in the United States. Mr. Kennedy’s nomination has prompted some to speak out.

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Patients who have had multiple COVID infections appear prone to contracting long COVID

A new study that identified 475 patients with post-acute sequelae of COVID-19 (PASC), also known as long COVID, revealed that nearly 85% (403) of these patients had multiple COVID-19 infections over the course of a four-year period (March 2020 to February 2024). Additionally, vaccination independently reduced the risk of long COVID in patients who had received the vaccination prior to contracting the infection.

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Public health experts, scientists warn senators on confirming RFK Jr

A new coalition of more than 700 public health professionals, scientists and activists signed an open letter to oppose Senate confirmation of Robert F. Kennedy Jr. as health secretary, saying his “fringe” views and inexperience would put the country at serious risk from severe infectious diseases.

The letter from the coalition called “Defend Public Health” said Kennedy’s “unfounded, fringe beliefs could significantly undermine public health practices across the country and around the world.”

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First Bird Flu Death in U.S. Reported in Louisiana

A Louisiana patient who had been hospitalized with severe bird flu has died, the first such fatality in the United States, state health officials reported on Monday.

The patient was older than 65 and had underlying medical conditions, the officials said. The individual became infected with the bird flu virus, H5N1, after exposure to a backyard flock and wild birds.

There is no sign that the virus is spreading from person to person anywhere in the country, and Louisiana officials have not identified any other cases in the state. Pasteurized dairy products remain safe to consume.

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