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WHO member states agree to landmark accord on future pandemic responses

Countries united under the World Health Organization on Wednesday agreed to a milestone accord on how to respond to future pandemics and avoid repeating the mistakes made during the Covid-19 crisis. The agreement comes despite US foreign aid cuts and possible tariffs on pharmaceuticals casting uncertainty over the talks.

Years of negotiations culminated early Wednesday with countries agreeing the text of a landmark accord on how to tackle future pandemics, aimed at avoiding a repeat of the mistakes made during the Covid-19 crisis.

After more than three years of talks and one last marathon session, weary delegates at the World Health Organization’s headquarters sealed the deal at around 2am (0000 GMT) Wednesday.

“Tonight marks a significant milestone in our shared journey towards a safer world,” WHO chief Tedros Adhanom Ghebreyesus said.

“The nations of the world made history in Geneva today.”

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Measles is spreading in Ontario — here’s what you need to know

A major outbreak of measles has infected more than 800 people in Ontario. It’s the first outbreak of its size since the disease was declared eliminated in 1998.

Now, lower vaccination rates are leading to a serious outbreak in the province, enough to garner a travel advisory to the province from New York State south of the border.

Here’s what you need to know about measles — how it’s transmitted, how you can protect yourself, and whether you need to update your vaccinations.

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Seniors 75 and over invited to get COVID-19 vaccine

(Montreal) A COVID-19 vaccination campaign is launched this spring for people at risk of developing complications, Santé Québec announced on Monday.

Teams are currently deployed in the province’s long-term care homes, after which vaccination will be offered in private seniors’ residences (RPA) with a more vulnerable clientele.

In addition to CHSLDs and RPAs, seniors 75 years of age or older and people with immunodeficiency or dialysis are encouraged to go get their vaccine dose. This vaccination campaign also aims to reach people aged 65-74 who live with a chronic disease or in remote and isolated areas.

Non-targeted people aged 6 months and older can also receive the COVID-19 vaccine free of charge, says Santé Québec. If they have already been vaccinated, they should wait at least six months after their vaccine before receiving a new dose.

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Is Covid Rewriting the Rules of Aging? Brain Decline Alarms Doctors

Five years after the pandemic’s start, millions of Americans are still struggling with long-lasting symptoms of Covid-19. Cognitive difficulties are among the most troubling and common symptoms in people both old and young.

These ailments can be severe enough to leave former professionals like Ken Todd unable to work and even diagnosed with a form of mild cognitive impairment.

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Health secretary RFK Jr. declares certain vaccines have ‘never worked,’ flummoxing scientists

Health secretary Robert F. Kennedy Jr. has expressed another unorthodox view on vaccines, with the long-time vaccine critic declaring that vaccines for respiratory bugs that target a sole part of the pathogen they are meant to protect against do not work.

The claim was dismissed as erroneous by vaccine experts, who were befuddled by the secretary’s theory, espoused during an interview with CBS News.

Kennedy made the claim in explaining a controversial recent decision by political appointees at the Food and Drug Administration to delay granting a full license to Novavax’s Covid-19 vaccine, which is still given under an emergency use authorization or EUA.

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Ontario measles case count exceeds 800 total infections, 155 new since last week

TORONTO – Ontario is reporting 155 new measles cases over the last week, pushing the province’s case count to 816 since an outbreak began in the fall.

The number of new cases has increased again after a few weeks of appearing to stabilize in the 100-per-week range, which public health physicians had taken as a sign of potential optimism.

Dr. Sarah Wilson, public health physician at Public Health Ontario, says the fact that Ontario has exceeded 800 cases is striking.

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How Trump 2.0 is slashing NIH-backed research — in charts

The US National Institutes of Health (NIH) has terminated nearly 800 research projects at a breakneck pace, wiping out significant chunks of funding to entire scientific fields, finds a Nature analysis of the unprecedented cuts.

The administration of US President Donald Trump began purging NIH-funded studies on topics that it deems problematic less than 50 days ago, continuously expanding its list to include research on topics ranging from COVID-19 to misinformation. Hundreds of the 30,000-plus scientists funded by the NIH yearly have been forced to halt their work after receiving notices that their research “no longer effectuates agency priorities”, and some have had to fire personnel or even shut down their laboratories.

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Studies: 1 in 7 US working-age adults report long COVID, with heaviest burden on the poor

Nearly 1 in 7 working-age US adults had experienced long COVID by late 2023, and socially disadvantaged adults were over 150% more likely to have persistent symptoms, two new studies find.

Future public health, economic burdens

Yesterday in Communications Medicine, Daniel Kim, MD, DrPH, of Northeastern University, analyzed data from the US Census Bureau’s Household Pulse Survey from September and November 2022 and August to October 2023 on more than 375,000 US adults, including nearly 50,000 with self-reported long COVID.

Kim assessed sociodemographic and socioeconomic factors as predictors of long COVID; estimated the risk of unemployment, financial difficulties, and anxiety and depression among working-age adults (ages 18 to 64 years) and those currently experiencing lingering symptoms; and tallied the economic effects of the resulting lost wages.

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Tackling the ‘silent pandemic’: breakthrough study puts first long COVID treatment on horizon

Researchers have shown a new drug compound can prevent long COVID symptoms in mice – a landmark finding that could lead to a future treatment for the debilitating condition.

The world-first study found mice treated with the antiviral compound, developed by a multidisciplinary research team at WEHI, were protected from long term brain and lung dysfunction – key symptoms of long COVID.

Researchers hope the unprecedented results could lead to clinical trials and the first treatment for the disease in the future.

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Airborne Danger

Stuffy, crowded classrooms mean kids are breathing in viruses and pollution. Parents are trying to make the air safer, but hitting roadblocks.

In September 2023, Heather Pun started sending her son to school with a carbon dioxide monitor. He was spending his days in a stuffy portable classroom, and she worried that COVID was being passed lung-to-lung through the stale air.

The device, which reads the concentration of carbon dioxide (CO2) in the air, showed CO2 levels as high as 3,500 parts per million (ppm) in his classroom.

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Top scientists pen letter calling for end to ‘assault on U.S. science’

Nearly 2,000 doctors, researchers, and scientists have signed an open letter calling for an end to what they describe as the Trump administration’s “wholesale assault on U.S. science.”

The letter, written by 13 scientists from disciplines including medicine, climate science and economics, urges Americans to demand their Congress protect scientific funding and integrity.

The signatories, all members of the National Academies of Sciences, Engineering, and Medicine, wrote that the Trump administration is “destabilizing this enterprise by gutting funding for research, firing thousands of scientists, removing public access to scientific data, and pressuring researchers to alter or abandon their work on ideological grounds.”

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Rollout of ‘miracle’ HIV prevention drug is threatened by Trump cuts to global AIDS relief program

The Trump administration’s enormous cuts to a global AIDS relief program threaten to upend the planned rollout of a groundbreaking HIV prevention drug that was expected to save countless lives.

The medicine, lenacapavir, made by Gilead Sciences, has caused a stir because clinical trial data showed a single set of injections every six months could provide virtually complete protection against infection, a form of prevention known as pre-exposure prophylaxis, or (PrEP). The drug, which is under regulatory review, has raised hopes that the deadly infectious disease can be mitigated around the globe. Early data for an even newer formulation suggest it might need to be given only once a year. “This is magical,” UNAIDS chief Winnie Byanyima declared last year.

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‘Abandoned and betrayed’: Removal of mask requirement in B.C. health care sparks outcry

We’ve come a long way from the days of general mask mandates for the public, but a recent move to eliminate the requirement in B.C. health care settings is causing some outcry.

According to a recent BC Ministry of Health release, “People are still encouraged to wear medical masks in health care settings as appropriate,” but it is not mandatory.

Some groups, including Protect Our Province BC and DoNoHarm BC, are questioning the decision. This response comes after B.C. announced that it was launching the spring immunization campaign on April 8.

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COVID-19 boosters help avoid breakthrough infections in immunocompromised people, McGill-led study finds

Researchers focused on those with rheumatoid arthritis, lupus, inflammatory bowel disease, multiple sclerosis and other immune-mediated inflammatory diseases

New research findings provide solid evidence that annual COVID-19 vaccine booster doses continue to be advisable for certain immunocompromised people, researchers at McGill University say.

The researchers looked at how often people with immune-mediated inflammatory diseases (IMIDs) got COVID-19 despite having received at least three doses of an mRNA COVID-19 vaccine. IMIDs – including rheumatoid arthritis, lupus, inflammatory bowel disease and multiple sclerosis – affect more than seven million Canadians. The medications they take often weaken their vaccine responses, increasing their vulnerability to infection.

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Spring COVID-19 vaccine doses expected for some vulnerable Albertans

Preparations are underway for a limited spring COVID-19 vaccination program in Alberta.

Pharmacists say certain groups of high-risk Albertans will be eligible for a biannual dose of the KP.2 vaccine, starting April 28.

Eligible groups include seniors (aged 65 and older), all First Nations, Métis and Inuit people six months of age and older, immunocompromised Albertans six months and up, and adults living in care homes, according to Alberta’s updated immunization policy.

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Trump’s proposed tariffs likely to cause shortages of Canadian-made drugs in U.S., study says

U.S. President Donald Trump’s proposed tariffs on pharmaceuticals are likely to cause shortages of dozens of Canadian-made drugs in the United States, according to a new study.

Pharmaceuticals are one of a handful of sector-specific tariffs the President has talked publicly about imposing, along with ones already levied on steel, aluminum and autos. Mr. Trump has suggested tariffs could address high drug costs in the U.S. and increase domestic manufacturing.

New research published Monday in the Journal of the American Medical Association looked at how many and what kind of Canadian-made drugs would be hit by the tariffs. It found US$3-billion in annual sales came from drugs with final production in Canada, which would lead to an increased cost of US$750-million for American buyers if tariffs were set at 25 per cent. Of the Canadian-made drugs, 79 per cent were generics.

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Province Offers COVID-19 Booster Doses to At-Risk Populations

The provincial government has started offering COVID-19 booster doses to specific at-risk populations, as identified by the National Advisory on Immunization.

Eligible are all people age 65 and older, adult residents of long-term care homes and other congregate living settings for seniors, and people who are over six months old and are moderately to severely immunocompromised.

The vaccine will be available until June 1st.

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The pandemic didn’t end for this P.E.I. woman, who wants more support for those with long COVID

Just over two years ago, Nikkie Gallant never would have imagined that simply sitting up in bed would be an exhausting task for her.

That’s been the P.E.I. musician’s reality since the fall of 2022, when she was diagnosed with post-COVID condition, more commonly known as “long COVID.”

Now she drains a lot of energy just going to the sink for a glass of water or folding laundry. She often has to forget about plans to leave the house.

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