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Long COVID: 3 years in

March 11 marks 3 years since WHO declared COVID-19 to be a pandemic. While the world is determined to move on from the acute phase, at least 65 million people are estimated to struggle with long COVID, a debilitating post-infection multisystem condition with common symptoms of fatigue, shortness of breath, and cognitive dysfunction, impairing their ability to perform daily activities for several months or years. Although the majority of patients infected with SARS-CoV-2 recover within a few weeks, long COVID is estimated to occur in 10–20% of cases and affects people of all ages, including children, with most cases occurring in patients with mild acute illness. The consequence is widespread global harm to people’s health, wellbeing, and livelihoods—an estimated one in ten people who develop long COVID stop working, resulting in extensive economic losses.