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Tag: European Union

Eli Lilly says it will raise drug prices in Europe to ‘make them lower’ in U.S.

Eli Lilly said Thursday that it would increase the prices of medicines in Europe and other developed markets “in order to make them lower” in the U.S., an apparent response to the Trump administration’s calls to do so. It singled out the list price of its popular weight-loss drug in the U.K. as part of that effort.

The announcement is among the first moves by a major drugmaker to raise prices abroad in order to lower them in the U.S., in line with President Trump’s agenda. But it’s not clear if these actions would actually increase the amount of revenue that Lilly earns abroad, since governments and private providers that cover drugs often negotiate discounts off the list prices. Lilly did not immediately announce any new price reductions in the U.S.

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Lab-made sugar-coated particle blocks Covid-19 infection — Possible new treatment on the horizon

Groundbreaking research led by a Swansea University academic has revealed a synthetic glycosystem — a sugar-coated polymer nanoparticle — that can block Covid-19 from infecting human cells, reducing infection rates by nearly 99%.

The glycosystem is a specially designed particle that mimics natural sugars found on human cells. These sugars, known as polysialosides, are made of repeating units of sialic acid — structures that viruses often target to begin infection. By copying this structure, the synthetic molecule acts as a decoy, binding to the virus’s spike protein and preventing it from attaching to real cells.

Unlike vaccines, which trigger immune responses, this molecule acts as a physical shield, offering a novel approach to infection prevention.

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Analysis: 2024-25 COVID vaccines offered strong protection against worst outcomes in seniors

The 2024-25 COVID mRNA vaccines targeting JN.1 were highly effective in protecting against hospitalization and death for at least 4 months in a cohort of Danish citizens aged 65 and older by October 1, 2024. The new analysis estimating the vaccine efficacy (VE) of last season’s COVID vaccines was published earlier this week in The Lancet Infectious Diseases.

In total, 894,560 Danish residents were included in the study, with a median age of 76. By Jan 31, 2025, 820,229 (91.7%) of the participants had received a JN.1 vaccine. Among those without updated JN.1 vaccination (74,331), 278 COVID-19 hospitalizations and 84 deaths were observed during 25.6 million person-days.

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COVID hospitalization linked to cognitive impairment 2 years later

Almost 20% of people who were hospitalized for COVID-19 infections early in the pandemic still had signs of impairment with brain function 2 years after infection, finds a new study in Scientific Reports.

The study population came from Portugal, in a region hit hard by the first wave of the COVID-19 pandemic. Based on hospital admission episodes and SARS-CoV-2 infection status from March 2020 to February 2021, the authors identified four groups: group 1 (101) hospitalized for COVID-19 infections, group 2 (87) hospitalized but uninfected with COVID-19, group 3 (252) infected but not requiring hospitalization, and group 4 (258) uninfected and not hospitalized for any reason.

Cognitive assessments were conducted in two parts 2 years after infection, a general screening using the Montreal Cognitive Assessment and a subsequent neuropsychological assessment conducted by one of four psychologists if the score of the general screening was low. Overall, verbal memory, visual memory, executive functions, language, and information processing speed and attention were evaluated.

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Childhood vaccines were a global success story. Misinformation and other obstacles are slowing that progress, a study shows

Routine vaccines have prevented the deaths of about 154 million children around the world over the past 50 years, a new study shows, but efforts have been slowing recently, allowing for the growth of some vaccine-preventable diseases. This backslide could lead to many more unnecessary illnesses and deaths without an increased effort to vaccinate children and counter misinformation.

The report, published Tuesday in the medical journal The Lancet, says that over the past five decades, the World Health Organization’s Expanded Programme on Immunization has vaccinated more than 4 billion children. This doubling of global coverage of vaccines has prevented countless cases of tuberculosis, measles, polio, diphtheria, tetanus and pertussis.

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COVID-19 Disease Burden Remains Greater Than Influenza, Study Shows

Researchers in Denmark conducted a large-scale evaluation of the disease burdens associated with COVID-19 and influenza. Their conclusion? COVID-19 has a greater impact than influenza, resulting in more hospitalizations and deaths. These findings, they note, emphasize the continued need for a strong public health response.

COVID-19 Exhibits Greater Disease Burden Than Influenza

To compare the disease burden of COVID-19 and influenza, the researchers evaluated data available from Danish health registries from May 16, 2022 to June 7, 2024. The results were published in The Lancet Infectious Diseases. A commentary about the findings was published in the same issue of the journal.

During this period, the risk of hospitalization due to COVID-19 was approximately two times higher than the risk of hospitalization due to influenza. The risk of death was approximately three times higher. The researchers note that these increased risks were greater during the first year of the study period but still were evident during the second year. The risk of mortality, for example, was five times greater for COVID-19 during the first year of the study. That increased risk dropped during the second year, but COVID-19 still had a two and a half times greater risk of mortality than influenza.

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Scientists have lost their jobs or grants in US cuts. Foreign universities want to hire them

As the Trump administration cut billions of dollars in federal funding to scientific research, thousands of scientists in the U.S. lost their jobs or grants…

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COVID-19 vaccination reduces risk of ‘long COVID’ in adults

COVID-19 vaccination reduced the risk of developing ‘long COVID’ by approximately 27% in adults fully vaccinated before infection, according to a literature review carried out…

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Smartwatch Data: Study Finds Early Health Differences in Long COVID Patients

People who later experienced persistent shortness of breath or fatigue after a COVID infection were already taking significantly fewer steps per day and had a higher resting heart rate before contracting the virus, according to a CSH study published in npj Digital Medicine. This may indicate lower fitness levels or pre-existing conditions as potential risk factors

Between April 2020 and December 2022, over 535,000 people in Germany downloaded and activated the Corona Data Donation App (CDA). Of these, more than 120,000 voluntarily shared daily data from their smartwatches and fitness trackers with researchers, providing insights into vital functions such as resting heart rate and step count.

“These high-resolution data served as the starting point for our study,” explains CSH researcher Katharina Ledebur. “We were able to compare vital signs in 15-minute intervals before, during, and after a SARS-CoV-2 infection.”

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3 vaccine doses cut long-COVID risk by over 60%, analysis suggests

In a Swedish cohort, the risk of long COVID was much lower for vaccinated than unvaccinated participants in the year after infection, even when restricting the analyses to subgroups based on variant, age, sex, and previous infection status, estimates a study published last week in the Journal of Infectious Diseases.

Karolinska Institutet researchers in Stockholm analyzed data from five registries to compare rates of persistent COVID-19 symptoms, or post-COVID condition [PCC], in adults infected from January 2021 to February 2022 by vaccination status in the 14 days before infection. Follow-up was 365 to 660 days.

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Severe COVID-19 may be a risk factor for multiple sclerosis

COVID-19 may be a risk factor for multiple sclerosis (MS). This has been shown by new research at Örebro University and Örebro University Hospital, Sweden. The study is published in the journal Brain Communications.

“We saw a raised risk of MS among people who had severe COVID-19. However, only an extremely small number of people who had severe COVID-19 received a subsequent MS diagnosis,” says Scott Montgomery, professor in clinical epidemiology.

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Long COVID: SARS-CoV-2 Spike Protein Accumulation Linked to Long-Lasting Brain Effects

Researchers from Helmholtz Munich and Ludwig-Maximilians-Universität (LMU) have identified a mechanism that may explain the neurological symptoms of Long COVID. The study shows that the SARS-CoV-2 spike protein remains in the brain’s protective layers, the meninges, and the skull’s bone marrow for up to four years after infection. This persistent presence of the spike protein could trigger chronic inflammation in affected individuals and increase the risk of neurodegenerative diseases. The team, led by Prof. Ali Ertürk, Director at the Institute for Intelligent Biotechnologies at Helmholtz Munich, also found that mRNA COVID-19 vaccines significantly reduce the accumulation of the spike protein in the brain. However, the persistence of spike protein after infection in the skull and meninges offers a target for new therapeutic strategies.

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Tour de France Reinstates COVID-19 Measures as More Cases Emerge in the Peloton

The Tour de France has reinstated COVID-19 protective measures, requiring race organizers, media, and guests to wear masks when in contact with riders and team staff. This protocol was announced by race organizer ASO on Sunday morning after several recent COVID-19 cases among the peloton.

“In order to limit health risks, it is now compulsory to wear a mask in the various areas where you will be in contact with the riders and members of the cycling teams,” read the statement from the ASO.

Riders who have abandoned the race due to the virus include Tom Pidcock (INEOS Grenadiers), Juan Ayuso (UAE Team Emirates), and Michael Mørkøv (Astana-Qazaqstan). Geraint Thomas (INEOS Grenadiers) remains in the Tour despite testing positive, as the rules currently allow.

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Finland to start bird flu vaccinations for humans, in world first

Finland plans to offer preemptive bird flu vaccination as soon as next week to some workers with exposure to animals, health authorities said on Tuesday, making it the first country in the world to do so.

The Nordic country has bought vaccines for 10,000 people, each consisting of two injections, as part of a joint EU procurement of up to 40 million doses for 15 nations from manufacturer CSL Seqirus (CSL.AX).

The European Commission said Finland would be the first country to roll out the vaccine.

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COVID Patient’s Infection Lasts Record 613 Days—and Accumulated Over 50 Mutations

A Covid-19 patient with a weakened immune system incubated a highly mutated novel strain over 613 days before succumbing to an underlying illness, researchers in the Netherlands found.

The patient, a 72-year-old man with a blood disorder, failed to mount a strong immune response to multiple Covid shots before catching the omicron variant in February 2022. Detailed analysis of specimens collected from more than two dozen nose and throat swabs found the coronavirus developed resistance to sotrovimab, a Covid antibody treatment, within a few weeks, scientists at the University of Amsterdam’s Centre for Experimental and Molecular Medicine said. It later acquired over 50 mutations, including some that suggested an enhanced ability to evade immune defenses, they said.

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Probe links COVID spread to school bus riders from sick driver

The proportion of children infected with COVID-19 while riding a bus to a school in Germany was about four times higher than in peers who didn’t ride the bus, illustrating efficient transmission during multiple short rides on public transport, finds a study published this week in Emerging Infectious Diseases.

A team led by researchers from the Robert Koch Institute in Berlin and public health officials used surveillance data, lab analyses, case-patient and household interviews, a cohort study of all students in grades 1 to 4, and a cohort study of bus riders to investigate a 2021 COVID-19 outbreak that involved an infected bus driver and his passengers. The rides lasted 9 to 18 minutes, and multiple schools in a single district were involved.

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‘Long Covid’ sick pay scheme to end in move that will impact 120 healthcare workers

A dedicated sick pay scheme for people suffering from the effects of “long Covid” is due to end in two weeks’ time in a move which will affect around 120 healthcare workers.

In July 2022 the Government introduced a temporary scheme to provide special leave with pay for eligible staff suffering with the symptoms of long Covid, such as fatigue and exhaustion. While the scheme was previously extended following approval by the Department of Public Expenditure, it will now end on March 31st. The Department of Public Expenditure has told the Department of Health that no further extensions will be granted.

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Radio | New report fails to address Covid impacts for children

  • A Public Health Agency investigation into the effects of the Covid-19 pandemic on children’s health is facing criticism, as it does not address how Covid infections directly affected children and their families.
  • Instead, the Swedish Covid Association says attention in the report has been focused on how school closures and other restrictions affected children’s well-being.
  • Social Affairs and Public Health Minister Jakob Forssmed tells Swedish Radio News there are valid reasons for having a wide-ranging investigation.
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