Press "Enter" to skip to content

Tag: research

Canada enters 5th year of COVID-19. Are we falling short in treatment?

As Canada enters its fifth year navigating COVID-19, some experts and advocates are worried treatment options for the virus remain disappointingly inadequate.

Despite significant strides in understanding the virus, Jennifer Hulme, a 42-year-old emergency physician at the University Health Network in Toronto, says many Canadians suffering from long-term COVID-19 are left without many options.

She is one of them.

Comments closed

コロナ感染、心不全のリスク高まる可能性 理研など研究

On December 23, a research team from Riken and other institutes announced the results of a study showing that after infection with the novel coronavirus, the heart may be persistently infected with the virus and the risk of heart failure may increase, even if the patient does not develop noticeable heart disease. The team points to the possibility of a sharp increase in the number of heart failure patients in the near future and calls for countermeasures to be taken.

Infection with the novel coronavirus occurs when a protruding “spike protein” on the surface of the virus binds to the ACE2 receptor on the surface of human cells. According to the team, the heart is more likely to express ACE2 compared to other organs. It has also been reported that some people infected with the novel coronavirus have reduced cardiac function, but the detailed mechanism is not known.

Comments closed

Long COVID changes heart rate variability, study suggests

According to a small case-control study today in Scientific Reports, long COVID can affect heart rate variability (HRV) at rest and during deep breathing, adding to the evidence that persistent symptoms of the virus can be associated with cardiac and dysfunction of the autonomic nervous system (dysautonomia). This system regulates involuntary functions like heartbeat, blood pressure, and sweating.

The study, conducted by Brazilian researchers, included 21 patients with long COVID and 20 controls. Long COVID—defined by the authors as new or persistent symptoms experienced 12 or more weeks after infection—has been associated with heart palpitations, orthostatic intolerance (difficulty staying upright), dizziness, and syncope.

Comments closed

COVID contact-tracing study suggests length of exposure biggest factor in disease spread

An analysis of 7 million contacts of COVID-19 patients in the United Kingdom estimates that most transmissions resulted from exposures lasting 1 hour to several days and that households accounted for 40% of spread from spring 2021 to early 2022.

Comments closed

Early Paxlovid for COVID-19 halved death, hospitalization in new study

Starting the antiviral drug nirmatrelvir-ritonavir (Paxlovid) 0 or 1 day after COVID-19 symptom onset halved 28-day all-cause death and hospitalization rates compared with waiting 2 or more days, University of Hong Kong researchers report in Nature Communications.

Comments closed

WHO designates JN.1 as separate COVID-19 variant of interest

Due to its rapid growth and potential to add to the respiratory virus burden in Northern Hemisphere countries, the World Health Organization (WHO) today designated JN.1, part of the BA.2.86 SARS-CoV-2 lineage, as its own variant of interest.

The announcement came following an assessment from the WHO’s Technical Advisory Group on SARS-CoV-2 evolution.

Comments closed

This COVID study has been tracking immunity for 3 years. Now it’s running out of money

A long-running study into COVID-19 immunity has unearthed promising insights on the still-mysterious disease, one of its lead researchers says — but she’s concerned its funding could soon dry up.

The Stop the Spread project, a collaboration by the Ottawa Hospital Research Institute (OHRI) and the University of Ottawa, has been monitoring antibody responses to COVID-19 in hundreds of people since October 2020.

Comments closed

Study shows long COVID worse for patients than ‘long flu’

In the 18 months after a serious COVID-19 or seasonal influenza infection, patients are at a significant increased risk of death, hospital readmission, or health problems affecting a number of organs, though COVID patients are hit harder, according to a study published yesterday in The Lancet Infectious Diseases.

The study was led by Ziyad Al-Aly, MD, the chief of research and development at the VA St. Louis Health Care System and a clinical epidemiologist at Washington University. Al-Aly has been studying long COVID for the past 3 years, and has been interested in studying the differences between the acute and chronic phases of the disease.

Comments closed

Many Canadians have had long COVID for almost 4 years. Researchers say there’s hope

Four years ago, Sonja Mally was a busy tattoo artist with a photographic memory and penchant for long hikes.

Now, the 38-year-old Toronto woman considers it a good day if she can do a small drawing, muster the energy to walk around the block or “perform very basic tasks.”

“It’s a hard thing to have to explain to people why maybe one day you might be doing fine and the next day you can’t find the words to complete a sentence,” Mally said.

Comments closed

Le mystère entourant la COVID longue limite les capacités de traitements

Four years after the first cases of what was later called COVID-19, infections continue to spread and lead to new cases of long COVID. However,…

Comments closed

Medicago : Mitsubishi Chemical redonne 40 M $ et transfère la propriété intellectuelle

The Government of Canada has reached an agreement with Mitsubishi Chemical Group Corporation (MCG), Medicago’s parent company. This company will have to pay $40 million in addition to transferring the intellectual property developed by Medicago to the new Quebec company Aramis Biotechnologies.

Comments closed

1 in 9 Canadians have had ‘long COVID’: StatCan

About one in nine Canadian adults have had long-term symptoms from COVID-19 infection, according to a Statistics Canada report issued Friday.

That amounts to 3.5 million Canadians, it said.

Almost 80 per cent of those people with long-term symptoms have them for six months or more, the report said.

In addition, more than half of those who ever had long-term symptoms still had them as of June 2023.

Comments closed

Les maladies post-infection, comme la COVID longue, plus fréquentes qu’on le pense

Early in the pandemic, scientists warned that COVID-19 could cause long-term sequelae even after a mild infection. After all, at least a dozen other known pathogens cause post-infection syndromes. Why didn’t we see this problem coming, and possibly prevent millions of people from developing long COVID?

Comments closed

COVID-19 late in pregnancy linked to severe maternal health problems

A study yesterday in Open Forum Infectious Diseases shows women who have COVID-19 infections within a week before giving birth are at an increased risk for severe maternal morbidity (SMM) events, including acute renal failure and adult respiratory distress syndrome (ARDS).

Comments closed

Nearly half of COVID survivors in Africa have lingering symptoms, data reveal

A systematic review and meta-analysis estimates a nearly 50% long-COVID rate months after infection in Africa, with psychiatric conditions the most common manifestations.

Published today in Scientific Reports, the February 2023 literature search and analysis involved 25 observational, English language long-COVID studies with 29,213 infected African patients.

Comments closed

Study: School air sampling worked as well as other methods in tracking COVID, flu

Air sampling was as effective in monitoring COVID-19 and influenza A (IAV) activity as three other methods in a Wisconsin school district from September 2022 to January 2023, according to a study published today in JAMA Network Open.

Comments closed

Small study finds brain alterations after COVID Omicron infection

Researchers in China report thinning of the gray matter and other changes in certain parts of the brain in 61 men after COVID-19 Omicron infection.

For the study, published late last week in JAMA Network Open, the researchers evaluated 61 men before and after infection with the SARS-CoV-2 Omicron variant in January 2023. The men had been part of a larger cohort who had undergone magnetic resonance imaging (MRI) and neuropsychiatric screenings before infection in August and September 2022. Average age was 43 years.

Comments closed

‘Dramatic’ increases in younger Canadians’ deaths contributed to our reduced life expectancy

Amid a declining life expectancy across the country, new national data released this week show that years on from the beginning of the pandemic, COVID-19…

Comments closed