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Tag: United States

New studies estimate long-COVID rates, identify risk factors

As new variants continue to emerge and infect people, older adults remain highly vulnerable to long-term health effects from this pathogen. Continued multidisciplinary research is needed to understand and prevent long COVID to reduce morbidity and mortality and maintain quality of life in older adults.

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About 400 Million People Worldwide Have Had Long Covid, Researchers Say

About 400 million people worldwide have been afflicted with long Covid, according to a new report by scientists and other researchers who have studied the condition. The team estimated that the economic cost — from factors like health care services and patients unable to return to work — is about $1 trillion worldwide each year, or about 1 percent of the global economy.

The report, published Friday in the journal Nature Medicine, is an effort to summarize the knowledge about and effects of long Covid across the globe four years after it first emerged.

It also aims to “provide a road map for policy and research priorities,” said one author, Dr. Ziyad Al-Aly, the chief of research and development at the V.A. St. Louis Health Care System and a clinical epidemiologist at Washington University in St. Louis. He wrote the paper with several other leading long Covid researchers and three leaders of the Patient-Led Research Collaborative, an organization formed by long Covid patients who are also professional researchers.

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Long COVID is a $1 trillion problem with no cure. Experts plead for governments to wake up

For months, governmental officials around the world have appeared to want to forgo discussing the specter of long COVID. As a new review makes clear, that is wishful thinking—and the latest COVID variants may well kick long COVID into overdrive, a scenario that researchers and experts have been warning about for some time.

“I think they (government agencies) are itching to pretend that COVID is over and that long COVID does not exist,” says Ziyad Al-Aly, director of the Clinical Epidemiology Center at Veterans Affairs St. Louis Health Care System and lead author of the review. “It is much more pleasant to pretend as if emergency department visits and hospitalizations haven’t been rising sharply this summer.”

In a Nature Medicine review this week, Al-Aly and several other top researchers lay out a difficult truth: Long COVID has already affected an estimated 400 million people worldwide, a number the authors say is likely conservative, at an economic cost of about $1 trillion annually—equivalent to 1% of the global economy.

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COVID data quietly disappears while cases rise

California-based engineer and scientist Patrick Vaughan made a troubling discovery July 10. Dozens of facilities providing COVID-19 wastewater data went offline, seemingly overnight.

Vaughan had been following WastewaterSCAN, a national program that monitors wastewater for diseases. He noticed that 42 of the previously reporting 194 facilities suddenly displayed small blue triangles with the message “data is no longer collected from this site.” The development came just as people across the U.S. scrambled for information during a summer COVID wave that even infected President Joe Biden.

“This is a major blow to our COVID wastewater tracking abilities,” Vaughan told his followers in a video he posted the same day.

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Nassau Legislature approves act prohibiting mask wearing in some scenarios

The Nassau County Legislature passed the Mask Transparency Act Monday – a law that prohibits the wearing of masks in public in some scenarios.

Those over the age of 16 will not be allowed to wear masks, unless it is being worn for the person’s health, religion or celebratory purposes. Officials say police will be the ones to determine whether or not the masks are being used for those purposes.

Legislators explained their reasoning for supporting the measure during the hearing.

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Sanders Proposes ‘Moonshot’ Bill to Combat Long Covid Crisis

For far too long, millions of Americans suffering from long Covid have had their symptoms dismissed or ignored — by the medical community, by the media, and by Congress. That is unacceptable and has got to change.

The legislation that we have introduced finally recognizes that long Covid is a public health emergency and provides an historic investment into research, development, and education needed to counter the effects of this terrible disease. Congress must act now to ensure treatments are developed and made available for Americans struggling with long Covid. Yes. It is time for a long Covid moonshot.

— U.S. Senator Bernie Sanders, chair of the Senate Committee on Health, Education, Labor, and Pensions (HELP)
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SARS-CoV-2 widespread in Virginia wildlife, likely from people

An examination of 23 common wildlife species in Virginia finds evidence of SARS-CoV-infection in 6 and antibodies indicating previous infection in 5.

For the study, published today in Nature Communications, Virginia Tech researchers collected 789 nasal and oral swabs and 126 blood samples from animals live-trapped and released or being treated at wildlife rehabilitation centers in Virginia and Washington, DC, from May 2022 to September 2023.

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Wildfire smoke may increase the risk of dementia, study finds

A new US study has found that wildfire smoke may be worse for brain health than other types of air pollution and even increase the risk of dementia.

The findings, reported on Monday at the Alzheimer’s Association International Conference in Philadelphia, come as millions spent the weekend under air quality warnings from wildfires spewing smoke across the western US, including a huge wildfire in California that has grown to more than 360,000 acres.

At issue is fine particulate matter or PM 2.5 – tiny particles about 30 times smaller than the diameter of a human hair that can be inhaled deep into the lungs and move to the bloodstream. This pollution – from traffic, factories and fires – can cause or worsen heart and lung diseases, and the new study adds to evidence it may play some role in dementia, too.

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Colorado reports avian flu infections in 5 people who culled sick poultry

The Colorado Department of Public Health and Environment (CDPHE) has reported five human H5 avian influenza infections in workers who were part of the response to a recent large outbreak at a layer farm, four of which have been confirmed by the US Centers for Disease Control and Prevention (CDC).

Patients have eye, respiratory symptoms

The patients have mild illness, including conjunctivitis and common respiratory symptoms. None were hospitalized, according to statements from the CDPHE. Though officials haven’t said if the virus on the poultry farm is the same as the B3.13 genotype infecting dairy cattle, conjunctivitis has also been reported in four dairy farm workers over the past few months.

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Functional neurological disorder is not an appropriate diagnosis for people with long Covid

Long Covid — the name adopted for cases of prolonged symptoms after an acute bout of Covid-19 — is an umbrella diagnosis covering a broad range of clinical presentations and abnormal biological processes. Researchers haven’t yet identified a single or defining cause for some of the most debilitating symptoms associated with long Covid, which parallel those routinely seen in other post-acute infection syndromes. These include overwhelming fatigue, post-exertional malaise, cognitive deficits (often referred to as brain fog), and extreme dizziness.

Given the current gaps in knowledge, some neurologists, psychiatrists, and other clinicians in the United States, United Kingdom, and elsewhere have suggested that an existing diagnosis known as functional neurological disorder (FND) could offer the best explanation for many cases of this devastating illness.

We strongly disagree. Although prominent news outlets such as The New Republic and Slate have promoted this perspective, it is unwarranted to view long Covid through the lens of functional neurological disorder. Despite assertions of robust evidence from those most invested in promoting it, the FND construct is based largely on speculation and assumption. Successful treatments for long Covid are much more likely to emerge from investigations into the kinds of immunological, neurological, hormonal, and vascular differences that have already been documented than from the inappropriate imposition of an often ill-fitting diagnosis onto the broad swath of people with these prolonged symptoms.

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‘Visionary’ study finds inflammation, evidence of Covid virus years after infection

Remember when we thought Covid was a two-week illness? So does Michael Peluso, assistant professor of medicine at the University of California, San Francisco.

He recalls the rush to study acute Covid infection, and the crush of resulting papers. But Peluso, an HIV researcher, knew what his team excelled at: following people over the long term.

So they adapted their HIV research infrastructure to study Covid patients. The LIINC program, short for “Long-term Impact of Infection with Novel Coronavirus,” started in San Francisco at the very beginning of the pandemic. By April 2020, the team was already seeing patients come in with lingering illness and effects of Covid — in those early days still unnamed and unpublicized as long Covid. They planned to follow people’s progress for three months after they were infected with the virus.

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NIH announces launch of clinical trial for nasal COVID vaccine

The National Institutes of Health (NIH) yesterday announced the launch of a phase 1 trial of a nasal vaccine against COVID-19, which also marks the first National Institute for Allergy and Infectious Diseases (NIAID) trial conducted as part of the government’s Project NextGen—an effort designed to advance the development of next-generation vaccines against the disease.

In an NIH statement, NIAID Director Jeanne Marrazzo, MD, said first-generation COVID vaccines have greatly mitigated the toll of the disease and are still effective for preventing severe illness, hospitalization, and death. She added, however, that they aren’t as good at preventing illness and battling milder disease.

“With the continual emergence of new virus variants, there is a critical need to develop next-generation COVID-19 vaccines, including nasal vaccines, that could reduce SARS-CoV-2 infections and transmission,” she said.

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Avian influenza in the United States closely monitored by authorities

The rise in the number of cases of avian influenza on farms in the United States, the infection of cow herds and recent cases of transmission to human beings are of concern to Quebec and Canadian authorities, who say they are monitoring the situation very closely.

Avian influenza – specifically avian influenza of subtypes H5 and H7 – is a reportable disease in Quebec. Avian influenza is a zoonosis, meaning it can be transmitted from animals to humans.

Cases of avian influenza in humans remain very rare, but last spring three cases of human infection associated with infected dairy farms were reported in the United States. Two infected people had eye symptoms and the third person suffered a respiratory infection.

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Despite Covid surge, Los Angeles mayor considers mask ban at protests

As Covid cases rise across California, the Los Angeles mayor Karen Bass announced that city officials were exploring the legality of wearing masks at demonstrations.

The announcement came as a response to a pro-Palestinian protest outside a Los Angeles synagogue that made international headlines.

Bass, a Democrat, said at a press conference with local Jewish leaders on Monday that she would be seeking “several points of clarity” from the city attorney “around what are the parameters with protests: when permits are needed, whether or not people should be masked, and establishing clear lines of demarcation between what is legal and what is not.”

The move represents a stark reversal from 2020, when public health officials urged protesters to wear masks, and Democratic politicians embraced mask-wearing, while Donald Trump and many Republicans rejected masks and other public health measures.

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Summer COVID bump intensifies in L.A. and California, fueled by FLiRT variants

The new COVID-19 subvariants collectively nicknamed FLiRT are continuing to increase their dominance nationwide, fueling a rise in cases in Los Angeles County and growth in the coronavirus levels seen in California wastewater.

Taken together, the data point to a coronavirus resurgence in the Golden State — one that, while not wholly unexpected given the trends seen in previous pandemic-era summers, has arrived earlier and is being driven by even more transmissible strains than those previously seen.

It remains unclear how bad the COVID situation may get this summer, however. Doctors have said that by the Fourth of July, we may have a better feel for how the rest of the season will play out.

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Former director of the CDC predicts the next pandemic will be from bird flu

The former director of the US Centers for Disease Control and Prevention (CDC), Robert Redfield, has said that the next pandemic could be from bird flu.

The World Health Organization recently announced the first human death from bird flu in Mexico, and the virus has been found in cattle across the US.

“I really do think it’s very likely that we will, at some time, it’s not a question of if, it’s more of a question of when we will have a bird flu pandemic,” Redfield told NewsNation on Friday.

He added that the mortality rate is likely to be much higher from bird flu compared to Covid-19.

While the mortality rate was 0.6 per cent for Covid-19, Redfield said the mortality for the bird flu would probably be “somewhere between 25 and 50 per cent.”

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COVID is coming for Calif., and it’s already hitting the Bay Area the hardest

If you or any of your friends have gotten sick with COVID-19 recently, you’re not the only ones: Case rates are rising in the Bay Area and the proof is in the pipes. According to the California Department of Public Health, the region now has the most viral wastewater than anywhere else in California.

In an email to SFGATE, Amanda Bidwell, a wastewater researcher and data analyst at Stanford, said that over the past 21 days “consistently high concentrations” of SARS-CoV-2 have been detected in wastewater samples collected across San Francisco.

“Currently we are seeing some of the highest concentrations we’ve ever measured” at these locations, Bidwell continued. And across San Francisco, the levels are approaching those last seen in December and January. Because individuals shed the virus before getting tested, this method of monitoring wastewater helps predict upcoming surges while including data from those who are asymptomatic.

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Report: More than 200 symptoms tied to long COVID

Today a new report from the National Academies of Sciences, Engineering, and Medicine presents a number of conclusions about long-COVID diagnosis, symptoms, and impact on daily function, including that the condition can cause more than 200 symptoms, and that a positive COVID-19 test is not necessary to make a long-COVID diagnosis.

The findings are meant to guide the Social Security Administration (SSA) and are published one week before the National Academies of Sciences, Engineering, and Medicine is set to offer a new single definition of long COVID that can be used across US governmental groups as a way to streamline treating the condition in the years to come.

“This report offers a comprehensive review of the evidence base for how Long COVID may impact a patient’s ability to engage in normal activities, such as going to work, attending school, or taking care of their families,” said Victor J. Dzau, MD, president of the National Academy of Medicine, in a National Academies press release. “Its findings will be useful to anyone attempting to understand how Long COVID may affect the millions of people in the U.S. who have reported symptoms.”

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